AIMC Topic: Aged, 80 and over

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Prediction of biological age using machine learning.

PloS one
In response to Taiwan's rapidly aging population and the rising demand for personalized health care, accurately assessing individual physiological aging has become an essential area of study. This research utilizes health examination data to propose ...

Handwriting in Mild Cognitive Impairment: Reliability Assessment and Machine Learning-Based Screening.

JMIR aging
BACKGROUND: Mild cognitive impairment (MCI) is a precursor of dementia. Therefore, MCI identification and monitoring are crucial to delaying dementia onset. Given the limits of existing clinical tests, objective support tools are needed.

Mapping the impact: AI-driven quantification of geographic atrophy on OCT scans and its association with visual sensitivity loss.

The British journal of ophthalmology
BACKGROUND/AIMS: To examine the association between artificial intelligence (AI)-driven segmentation of geographic atrophy (GA) on optical coherence tomography (OCT) and visual sensitivity loss quantified by defect-mapping microperimetry, a testing s...

Linking dynamic connectivity states to cognitive decline and anatomical changes in Alzheimer's disease.

NeuroImage
Alterations in brain connectivity provide early indications of neurodegenerative diseases like Alzheimer's disease (AD). Here, we present a novel framework that integrates a Hidden Markov Model (HMM) within the architecture of a convolutional neural ...

Identifying determinants of readmission and death post-stroke using explainable machine learning.

PloS one
BACKGROUND: Stroke remains a global health challenge with high rates of mortality and rehospitalization placing significant demands on healthcare systems. Identifying factors that determine outcomes of post-hospitalization improves resource allocatio...

Biological Age Estimation From the Age Gap Using Deep Learning Integrating Morbidity and Mortality: Model Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Biological age (BA) is increasingly recognized as a valuable alternative to chronological age (CA) for assessing an individual's health and aging status. However, existing models are based on limited clinical parameters and have not thoro...

Cognitive prediction using regional connectivities and network biomarkers in Alzheimer's disease.

Neuroscience
Achieving a deep understanding of brain mechanisms requires multi-scale perspectives to capture the architecture of complex networks. In this study, we focused on patients with cognitive impairment and constructed individual brain networks from neuro...

AlzFormer: Video-based space-time attention model for early diagnosis of Alzheimer's disease.

Neuroscience
Early and accurate Alzheimer's disease (AD) diagnosis is critical for effective intervention, but it is still challenging due to neurodegeneration's slow and complex progression. Recent studies in brain imaging analysis have highlighted the crucial r...

Development and validation of a machine learning-based prediction model for frailty in older adults with diabetes: a study protocol for a retrospective cohort study.

BMJ open
INTRODUCTION: Frailty is a common condition in older adults with diabetes, which significantly increases the risk of adverse health outcomes. Early identification of frailty in this population is crucial for implementing timely interventions. However...