AIMC Topic: Alzheimer Disease

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A Lightweight Deep Convolutional Neural Network Extracting Local and Global Contextual Features for the Classification of Alzheimer's Disease Using Structural MRI.

IEEE journal of biomedical and health informatics
Recent advancements in the classification of Alzheimer's disease have leveraged the automatic feature generation capability of convolutional neural networks (CNNs) using neuroimaging biomarkers. However, most of the existing CNN-based methods often d...

AI-Driven Framework for Enhanced and Automated Behavioral Analysis in Morris Water Maze Studies.

Sensors (Basel, Switzerland)
The Morris Water Maze (MWM) is a widely used behavioral test to assess the spatial learning and memory of animals, particularly valuable in studying neurodegenerative disorders such as Alzheimer's disease. Traditional methods for analyzing MWM experi...

Applying machine learning to high-dimensional proteomics datasets for the identification of Alzheimer's disease biomarkers.

Fluids and barriers of the CNS
PURPOSE: This study explores the application of machine learning to high-dimensional proteomics datasets for identifying Alzheimer's disease (AD) biomarkers. AD, a neurodegenerative disorder affecting millions worldwide, necessitates early and accura...

Therapeutic Mechanisms of Medicine Food Homology Plants in Alzheimer's Disease: Insights from Network Pharmacology, Machine Learning, and Molecular Docking.

International journal of molecular sciences
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive function. Currently, there are no effective treatments for this condition. Medicine food homology plants have gained increasing atten...

Machine Learning Methods for Classifying Multiple Sclerosis and Alzheimer's Disease Using Genomic Data.

International journal of molecular sciences
Complex diseases pose challenges in prediction due to their multifactorial and polygenic nature. This study employed machine learning (ML) to analyze genomic data from the UK Biobank, aiming to predict the genomic predisposition to complex diseases l...

CSEPC: a deep learning framework for classifying small-sample multimodal medical image data in Alzheimer's disease.

BMC geriatrics
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder that significantly impacts health care worldwide, particularly among the elderly population. The accurate classification of AD stages is essential for slowing disease progression an...

Linguistic cues for automatic assessment of Alzheimer's disease across languages.

Journal of Alzheimer's disease : JAD
BackgroundMost common forms of dementia, including Alzheimer's disease, are associated with alterations in spoken language.ObjectiveThis study explores the potential of a speech-based machine learning (ML) approach in estimating cognitive impairment,...

Deep learning to quantify the pace of brain aging in relation to neurocognitive changes.

Proceedings of the National Academy of Sciences of the United States of America
Brain age (BA), distinct from chronological age (CA), can be estimated from MRIs to evaluate neuroanatomic aging in cognitively normal (CN) individuals. BA, however, is a cross-sectional measure that summarizes cumulative neuroanatomic aging since bi...

Identification of UBE2N as a biomarker of Alzheimer's disease by combining WGCNA with machine learning algorithms.

Scientific reports
Alzheimer's disease (AD) is the most common cause of dementia, emphasizing the critical need for the development of biomarkers that facilitate accurate and objective assessment of disease progression for early detection and intervention to delay its ...

Hyperfusion: A hypernetwork approach to multimodal integration of tabular and medical imaging data for predictive modeling.

Medical image analysis
The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can provide a com...