AIMC Topic: Analgesics, Opioid

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Air assisted emulsification liquid-liquid microextraction based on deep eutectic solvent for preconcentration of methadone in water and biological samples.

Talanta Nov 18, 2016
Nowadays, a deep eutectic solvent (DES) has recently been considered as a green ion liquid analogue. In this study, a new compound of DES has been synthesized as an extraction solvent in air assistedemulsification liquid-liquid microextraction method...
Limit of Detection Humans Liquid Phase Microextraction Water Pollutants, Chemical Analgesics, Opioid Methadone Solvents Calibration Air
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A study on the safety evaluation of buphrenorphine administered through an autoinjector compared with manual injection using haematological and biochemical variables in rats.

Human & experimental toxicology Oct 20, 2016
Buprenorphine drug cartridge was made for autoinjector device for use in emergency and critical situations to reduce the morbidity and mortality. Water-filled cartridges were prepared and buprenorphine was injected aseptically in the cartridge, to ma...
Injections Aspartate Aminotransferases Buprenorphine Female Animals Rats, Wistar Analgesics, Opioid
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Exchanging expertise and constructing boundaries: The development of a transnational knowledge network around heroin-assisted treatment.

The International journal on drug policy Dec 17, 2015
Over the last 20 years, supervised injectable and inhalable heroin prescribing has been developed, tested and in some cases introduced as a second line treatment for limited groups of entrenched heroin users in a number of European countries and Cana...
Heroin Dependence Evidence-Based Medicine Administration, Inhalation Public Opinion International Cooperation Stakeholder Participation Interdisciplinary Communication Qualitative Research Cooperative Behavior Humans Treatment Outcome Behavior, Addictive Injections, Intravenous Drug Users Analgesics, Opioid Heroin Knowledge Bases
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A Randomized, Double-Blind, Double-Dummy Study to Evaluate the Intranasal Human Abuse Potential and Pharmacokinetics of a Novel Extended-Release Abuse-Deterrent Formulation of Oxycodone.

Pain medicine (Malden, Mass.) Dec 14, 2015
OBJECTIVE: Evaluate the human abuse potential (HAP) of an experimental, microsphere-in-capsule formulation of extended-release oxycodone (oxycodone DETERx®) (herein "DETERx").
Analgesics, Opioid Opioid-Related Disorders Cross-Over Studies Delayed-Action Preparations Oxycodone Adult Humans Male Female Middle Aged Young Adult Double-Blind Method Administration, Intranasal
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Intranasal Abuse Potential, Pharmacokinetics, and Safety of Once-Daily, Single-Entity, Extended-Release Hydrocodone (HYD) in Recreational Opioid Users.

Pain medicine (Malden, Mass.) Dec 14, 2015
OBJECTIVES: A once-daily, extended-release hydrocodone bitartrate tablet with abuse-deterrent properties (Hysingla ER® [HYD]) is available for the treatment of chronic pain in appropriate patients. This study evaluated the intranasal abuse potential ...
Delayed-Action Preparations Administration, Intranasal Male Hydrocodone Middle Aged Cross-Over Studies Double-Blind Method Powders Analgesics, Opioid Illicit Drugs Opioid-Related Disorders Drug Administration Schedule Humans Female Young Adult Adult
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Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial.

Pain medicine (Malden, Mass.) Jul 14, 2015
OBJECTIVES: To test the hypotheses that lidocaine 5% patches decrease the severity of acute pain and incidence of persistent incisional pain after robotic cardiac valve surgery.
Female Aged Male Middle Aged Lidocaine Humans Pain, Postoperative Analgesics, Opioid Cardiac Surgical Procedures Analgesia, Patient-Controlled Patient Satisfaction Anesthetics, Local Robotics Pain Measurement Disability Evaluation Double-Blind Method Heart Valves Acute Pain Transdermal Patch
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Machine learning on encephalographic activity may predict opioid analgesia.

European journal of pain (London, England) Jun 11, 2015
BACKGROUND: Opioids are used for the treatment of pain. However, 30-50% of patients have insufficient effect to the opioid initially selected by the physician, and there is an urgent need for biomarkers to select responders to the most appropriate dr...
Analgesics, Opioid Morphine Pain Humans Female Young Adult Adult Male Middle Aged Support Vector Machine Electroencephalography
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Transversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy: a randomised clinical trial.

Acta anaesthesiologica Scandinavica May 31, 2015
BACKGROUND: Transversus abdominis plane (TAP) block is widely used as a part of pain management after various abdominal surgeries. We evaluated the effect of TAP block as an add-on to the routine analgesic regimen in patients undergoing robot-assiste...
Sodium Chloride Hysterectomy Pain, Postoperative Ropivacaine Analgesics, Opioid Humans Morphine Prospective Studies Analgesia, Patient-Controlled Robotics Female Adult Middle Aged Single-Blind Method Nerve Block Laparoscopy Amides Abdominal Muscles Anesthetics, Local
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Transversus abdominis plane block in robotic gynecologic oncology: a randomized, placebo-controlled trial.

Gynecologic oncology Nov 20, 2014
OBJECTIVE: Although robotic surgery decreases pain compared to laparotomy, postoperative pain can be a concern near the site of a larger assistant trocar site. The aim of this study was to determine the efficacy of transversus abdominis plane (TAP) b...
Aged Aged, 80 and over Young Adult Adult Middle Aged Linear Models Adolescent Genital Neoplasms, Female Nerve Block Nomograms Humans Treatment Outcome Anesthetics, Local Female Follow-Up Studies Robotics Pain Measurement Double-Blind Method Laparoscopy Pain, Postoperative Bupivacaine Analgesics, Opioid Morphine
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Chronic Pain Prevalence, Opioid Use, and Primary Care Provider Opioid Prescription Patterns in the U.S. from 2017 to 2019 Derived from Medicaid Claims Data.

Studies in health technology and informatics Aug 7, 2025
Chronic non-cancer pain (CNCP) is a major health concern in the United States, incurring substantial healthcare costs and frequently requiring opioid therapy in primary care. This retrospective cross-sectional study used Medicaid claims data from six...
Aged Young Adult Adult Cross-Sectional Studies Male Humans Retrospective Studies Female Analgesics, Opioid Practice Patterns, Physicians' Drug Prescriptions Chronic Pain Medicaid Middle Aged Prevalence Adolescent Primary Health Care United States
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