AIMC Topic: Anesthetics, Local

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A Histological Study of Vasoconstriction by Local Anesthetics in Mandible.

Anesthesia progress Jan 1, 2018
To assess the effect of epinephrine-containing local anesthetics on vasoconstriction, we immunohistochemically measured the intravascular lumen area in different regions of the mandible. Twelve male Wistar rats were used. General anesthesia was induc...
Vasoconstriction Biomarkers Vasoconstrictor Agents Rats, Wistar Injections Lidocaine Animals Actins Anesthetics, Local Male Epinephrine Muscle, Smooth, Vascular Mandible
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Fortacin™ Spray for the Treatment of Premature Ejaculation.

Urologia Dec 1, 2017
Premature ejaculation (PE) is a common complaint of male sexual dysfunction affecting men and their partners and consequently causing significant personal and interpersonal distress. Increased sensitivity of the glans penis and abnormalities of the a...
Premature Ejaculation Lidocaine, Prilocaine Drug Combination Humans Treatment Outcome Anesthetics, Local
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A Randomized Controlled Trial Study on the Effect of Adding Dexmedetomidine to Bupivacaine in Supraclavicular Block Using Ultrasound Guidance.

Ethiopian journal of health sciences Nov 1, 2016
BACKGROUND: The benefits of regional anesthetic techniques are well established. Use of additives to local anesthetics can prolong these benefits. The aim of this study was to find out the effect of adding dexmedetomidine to bupivacaine for supraclav...
Adult Male Middle Aged Hemodynamics Humans Female Bupivacaine Drug Therapy, Combination Time Factors Brachial Plexus Block Anesthetics, Local Analgesia Double-Blind Method Analgesics, Non-Narcotic Dexmedetomidine
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Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain.

Acta pharmaceutica (Zagreb, Croatia) Jun 1, 2016
A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (...
Solubility Drug Compounding Technology, Pharmaceutical Hypromellose Derivatives Anesthetics, Local Models, Chemical Kinetics Tablets Adhesiveness Mouth Mucosa Administration, Buccal Humans Cyclooxygenase Inhibitors Neural Networks, Computer Toothache Alginates Lidocaine Flurbiprofen Glucuronic Acid Hexuronic Acids
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Pharmacodynamics and Pharmacokinetics of Levobupivacaine Used for Epidural Anesthesia in Patients with Liver Dysfunction.

Cell biochemistry and biophysics Dec 1, 2015
The objective of this study was to study the pharmacodynamics and pharmacokinetics of levobupivacaine used for epidural anesthesia in patients with liver dysfunction. Twenty patients aged 20-60, American Society of Anesthesiologists (ASA) graded I-II...
Spinal Nerves Liver Diseases Anesthesia, Epidural Metabolic Clearance Rate Tissue Distribution Levobupivacaine Middle Aged Anesthetics, Local Bupivacaine Sensation Humans Female Adult Male
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[ED50 of Intrathecal Isobaric Bupivacaine with Epidural Volume Extension for Cesarean Delivery].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Nov 1, 2015
OBJECTIVE: To determine the 50% effective dose (ED50) of intrathecal isobaric bupivacaine in combined spinal-epidural anaesthesia with epidural volume extension for caesarean surgery.
Humans Prospective Studies Sodium Chloride Anesthetics, Local Anesthesia, Epidural Double-Blind Method Pregnancy Bupivacaine Female Anesthesia, Spinal Cesarean Section Logistic Models
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Radial artery blood gas sampling: a randomized controlled trial of lidocaine local anesthesia.

Journal of evidence-based medicine Nov 1, 2015
BACKGROUND: Radial artery puncture is a common procedure and yet the role of local anesthesia for reducing the pain of this procedure continues to be debated. Clinical practice is variable and there is potential for substantial financial savings. Thi...
Anesthesia, Local Punctures Blood Gas Analysis Radial Artery Phlebotomy Humans Female Lidocaine Anesthetics, Local Pain Male Middle Aged
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Ultrasound-guided subcostal transversus abdominis plane infiltration with liposomal bupivacaine for patients undergoing robotic-assisted hysterectomy: a retrospective study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society Jun 1, 2015
OBJECTIVE: We sought to determine the effect of a subcostal transversus abdominis plane (TAP) block with liposomal bupivacaine on postoperative maximal pain score and length of hospital stay among women undergoing robotic-assisted hysterectomy.
Humans Prognosis Retrospective Studies Ultrasonography, Interventional Abdominal Muscles Pain, Postoperative Follow-Up Studies Liposomes Female Bupivacaine Hysterectomy Middle Aged Anesthetics, Local Length of Stay Robotics Nerve Block Laparoscopy
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The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection.

Turkish journal of medical sciences Jan 1, 2015
BACKGROUND/AIM: To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection.
Drug Therapy, Combination Intervertebral Disc Displacement Low Back Pain Tramadol Lumbar Vertebrae Analgesics Administration, Oral Injections, Epidural Triamcinolone Acetonide Visual Analog Scale gamma-Aminobutyric Acid Amines Cyclohexanecarboxylic Acids Gabapentin Adult Male Middle Aged Glucocorticoids Anesthetics, Local Disability Evaluation Single-Blind Method Bupivacaine Humans Prospective Studies Female
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