AIMC Topic: Animals

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Machine learning reveals correlations between brain age and mechanics.

Acta biomaterialia
Our brain undergoes significant micro- and macroscopic changes throughout its life cycle. It is therefore crucial to understand the effect of aging on the mechanical properties of the brain in order to develop accurate personalized simulations and di...

Optimizing lipid nanoparticles for fetal gene delivery in vitro, ex vivo, and aided with machine learning.

Journal of controlled release : official journal of the Controlled Release Society
There is a clinical need to develop lipid nanoparticles (LNPs) to deliver congenital therapies to the fetus during pregnancy. The aim of these therapies is to restore normal fetal development and prevent irreversible conditions after birth. As a firs...

Computational staining of CD3/CD20 positive lymphocytes in human tissues with experimental confirmation in a genetically engineered mouse model.

Frontiers in immunology
INTRODUCTION: Immune dysregulation plays a major role in cancer progression. The quantification of lymphocytic spatial inflammation may enable spatial system biology, improve understanding of therapeutic resistance, and contribute to prognostic imagi...

A comprehensive evaluation of an artificial intelligence based digital pathology to monitor large-scale deworming programs against soil-transmitted helminths: A study protocol.

PloS one
BACKGROUND: Manual screening of a Kato-Katz (KK) thick stool smear remains the current standard to monitor the impact of large-scale deworming programs against soil-transmitted helminths (STHs). To improve this diagnostic standard, we recently design...

Deep Learning With Optical Coherence Tomography for Melanoma Identification and Risk Prediction.

Journal of biophotonics
Malignant melanoma is the most severe skin cancer with a rising incidence rate. Several noninvasive image techniques and computer-aided diagnosis systems have been developed to help find melanoma in its early stages. However, most previous research u...

A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS-Based Microparticles in a Breast Cancer Model.

ACS nano
Multimodal cancer therapies are often required for progressive cancers due to the high persistence and mortality of the disease and the negative systemic side effects of traditional therapeutic methods. Thus, the development of less invasive modaliti...

MPE-HRNet: A Lightweight High-Resolution Network for Multispecies Animal Pose Estimation.

Sensors (Basel, Switzerland)
Animal pose estimation is crucial for animal health assessment, species protection, and behavior analysis. It is an inevitable and unstoppable trend to apply deep learning to animal pose estimation. In many practical application scenarios, pose estim...

Omics in IgG4-related disease.

Chinese medical journal
Research on IgG4-related disease (IgG4-RD), an autoimmune condition recognized to be a unique disease entity only two decades ago, has processed from describing patients' symptoms and signs to summarizing its critical pathological features, and furth...

A Bio-Inspired Magnetic Soft Robotic Fish for Efficient Solar-Energy Driven Water Purification.

Small methods
Solar-driven water evaporation is a promising solution for global water scarcity but is still facing challenges due to its substantial energy requirements. Here, a magnetic soft robotic bionic fish is developed by combining magnetic nanoparticles (Fe...

Quality evaluation parameter and classification model for effluents of wastewater treatment plant based on machine learning.

Water research
With the growing consensus of emerging pollutants and biological toxicity risks in wastewater treatment plant (WWTP) effluents, traditional water quality management based on general chemical parameters no longer meets the new challenges. Here, a firs...