AIMC Topic: Animals

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Recent advances in culture medium design for enhanced production of monoclonal antibodies in CHO cells: A comparative study of machine learning and systems biology approaches.

Biotechnology advances
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells has revolutionized the treatment of numerous diseases, solidifying their position as a cornerstone of the biopharmaceutical industry. However, achieving maximum mA...

Machine learning approach in canine mammary tumour classification using rapid evaporative ionization mass spectrometry.

Analytical and bioanalytical chemistry
Rapid evaporative ionization mass spectrometry (REIMS) coupled with a monopolar handpiece used for surgical resection and combined with chemometrics has been previously explored by our research group (Mangraviti et al. in Int J Mol Sci 23(18):10562, ...

Automated Single Cell Phenotyping of Time-of-Flight Secondary Ion Mass Spectrometry Tissue Images.

Journal of the American Society for Mass Spectrometry
Existing analytical techniques are being improved or applied in new ways to profile the tissue microenvironment (TME) to better understand the role of cells in disease research. Fully understanding the complex interactions between cells of many diffe...

Optimization and control of robotic vertebral plate grinding: Predictive modeling, parameter optimization, and fuzzy control strategies for minimizing bone damage in laminectomy procedures.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
During the robotic grinding of vertebral plates in high-risk laminectomy procedures, programmed operations may inadvertently induce force or temperature-related damage to the bone tissue. Therefore, it is imperative to explore a control methodology a...

Identification of movie encoding neurons enables movie recognition AI.

Proceedings of the National Academy of Sciences of the United States of America
Natural visual scenes are dominated by spatiotemporal image dynamics, but how the visual system integrates "movie" information over time is unclear. We characterized optic tectal neuronal receptive fields using sparse noise stimuli and reverse correl...

Convolutional neural network for oral cancer detection combined with improved tunicate swarm algorithm to detect oral cancer.

Scientific reports
Early Diagnosis of oral cancer is very important and can save you from some oral malignancies. However, while this approach aids in the rapid healing of patients and the preservation of their lives, there are several causes for poor and wrong diagnos...

3D Printing of a Biomimetic Myotendinous Junction Assisted by Artificial Intelligence.

Biomaterials science
The myotendinous junction (MTJ) facilitates force transmission between muscle and tendon to produce joint movement. The complex microarchitecture and regional mechanical heterogeneity of the myotendinous junction pose major challenges in creating thi...

Antibiotic resistance in : mechanisms and emerging treatment.

Critical reviews in microbiology
, able to survive on the surfaces of medical devices, is a life-threatening pathogen that mainly leads to nosocomial infection especially in immunodeficient and cystic fibrosis (CF) patients. The antibiotic resistance in has become a world-concernin...

MMD-Net: Image domain multi-material decomposition network for dual-energy CT imaging.

Medical physics
BACKGROUND: Multi-material decomposition is an interesting topic in dual-energy CT (DECT) imaging; however, the accuracy and performance may be limited using the conventional algorithms.

Magnetic soft microrobots for erectile dysfunction therapy.

Proceedings of the National Academy of Sciences of the United States of America
Erectile dysfunction (ED) is a major threat to male fertility and quality of life, and mesenchymal stromal cells (MSCs) are a promising therapeutic option. However, therapeutic outcomes are compromised by low MSC retention and survival rates in corpu...