AIMC Topic: Animals
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Dynamics and design of passive tails for enhanced stability of motion.
Bioinspiration & biomimetics
Jun 6, 2025
In this work, we study the nonlinear dynamics of tail motion using numerical simulations and experiments. Our simulations are based on a discrete model comprising rigid cylinders (representing vertebrae) coupled by longitudinal, shear, and bending sp...
Spatial reasoning via recurrent neural dynamics in mouse retrosplenial cortex.
Nature neuroscience
Jun 6, 2025
From visual perception to language, sensory stimuli change their meaning depending on previous experience. Recurrent neural dynamics can interpret stimuli based on externally cued context, but it is unknown whether they can compute and employ interna...
Fusing multisensory signals across channels and time.
PLoS computational biology
Jun 6, 2025
Animals continuously combine information across sensory modalities and time, and use these combined signals to guide their behaviour. Picture a predator watching their prey sprint and screech through a field. To date, a range of multisensory algorith...
Specificity protein 1 suppresses prohibitin 1 to induce macrophage M1 polarization and impair phagocytosis, exacerbating sepsis-associated acute lung injury.
Free radical biology & medicine
Jun 5, 2025
Sepsis-related acute lung injury (ALI) is a severe and life-threatening complication characterized by excessive inflammation and immune dysfunction. Macrophages play a central role in the pathogenesis of ALI, with dysregulated polarization and impair...
The latest advances with natural products in drug discovery and opportunities for the future: a 2025 update.
Expert opinion on drug discovery
Jun 5, 2025
INTRODUCTION: The landscape of drug discovery is rapidly evolving, with natural products (NPs) playing a pivotal role in the development of novel therapeutics. Despite their historical significance, challenges persist in fully harnessing their potent...
Construction of a deep learning-based predictive model to evaluate the influence of mechanical stretching stimuli on MMP-2 gene expression levels in fibroblasts.
Biomedical engineering online
Jun 5, 2025
BACKGROUND: Matrix metalloproteinase-2 (MMP-2) secretion homeostasis, governed by the multifaceted interplay of skin stretching, is a pivotal determinant influencing wound healing dynamics. This investigation endeavors to devise an artificial intelli...
Encoding flexible gait strategies in stick insects through data-driven inverse reinforcement learning.
Bioinspiration & biomimetics
Jun 5, 2025
Stick insects exhibit remarkable adaptive walking capabilities across diverse environments; however, the mechanisms underlying their gait transitions remain poorly understood. Although reinforcement learning (RL) has been employed to generate insect-...
Underwater bionic undulating fins incorporating thickness effects: hydrodynamic performance and optimal thickness variation rate analysis.
Bioinspiration & biomimetics
Jun 5, 2025
In response to the urgent issues faced by current bionic undulating fin robot propulsion mechanisms, such as low working efficiency, insufficient swimming speed, ignoring thickness parameters, and the need for further improvement in biomimetic degree...
Vascular segmentation of functional ultrasound images using deep learning.
Computers in biology and medicine
Jun 4, 2025
Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound (fUS), have...
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping.
ACS nano
Jun 4, 2025
Current clinical treatment of pulmonary diseases requires an advanced three-dimensional (3D) pathological atlas of the microenvironment, particularly the trachea, which is predominantly affected by lung disorders. In this study, the gridded cyclodext...
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