AIMC Topic: Animals
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Predicting viral host codon fitness and path shifting through tree-based learning on codon usage biases and genomic characteristics.
Scientific reports
Apr 10, 2025
Viral codon fitness (VCF) of the host and the VCF shifting has seldom been studied under quantitative measurements, although they could be concepts vital to understand pathogen epidemiology. This study demonstrates that the relative synonymous codon ...
Smart MXene-based microrobots for targeted drug delivery and synergistic therapies.
Nanoscale
Apr 10, 2025
MXenes and their composites exhibit remarkable electrical conductivity, mechanical flexibility, and biocompatibility, making them ideal candidates for microrobot fabrication. Their tunable surface chemistry allows for easy functionalization, which en...
Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.
PloS one
Apr 10, 2025
BACKGROUND: The allelic variations of the apolipoprotein E (APOE) gene play a critical role in regulating lipid metabolism and significantly impact cardiovascular disease risk (CVD). This study aimed to evaluate the impact of exercise on cardiac stru...
MXene-enabled organic synaptic fiber for ultralow-power and biochemical-mediated neuromorphic transistor.
Biosensors & bioelectronics
Apr 9, 2025
Fibrous bioelectronic provides an intrinsically accessible platform for artificial nerve and real-time physiological perception. However, advanced fiber-based artificial synapse remains a challenge due to the contradictory conductance demands for bra...
Exploring 4 generation EGFR inhibitors: A review of clinical outcomes and structural binding insights.
European journal of pharmacology
Apr 9, 2025
Epidermal growth factor receptor (EGFR) is a potential target for anticancer therapies and plays a crucial role in cell growth, survival, and metastasis. EGFR gene mutations trigger aberrant signaling, leading to non-small cell lung cancer (NSCLC). T...
Ivermectin performance against equine strongylids: Efficacy, egg reappearance periods, and fecal egg counting method comparison.
Veterinary parasitology
Apr 9, 2025
Equine strongylids are ubiquitous and can cause severe health issues. Anthelmintic resistance is widely common in cyathostomin parasites, and recent studies have documented increasing incidence of resistance to the macrocyclic lactone drug class. Sev...
Accelerometer-derived classifiers for early detection of degenerative joint disease in cats.
Veterinary journal (London, England : 1997)
Apr 9, 2025
Decreased mobility is a clinical sign of degenerative joint disease (DJD) in cats, which is highly prevalent, with 61 % of cats aged six years or older showing radiographic evidence of DJD. Radiographs can reveal morphological changes and assess join...
Wireless motion control of a swimming eel-machine hybrid robot.
Bioinspiration & biomimetics
Apr 9, 2025
This study presents a flexible aquatic swimming robot, which is a promising candidate for underwater search and detection missions. The robot is a living eel fitted with a wireless electronic backpack stimulator attached to its dorsal region. Leverag...
PursuitNet: A deep learning model for predicting competitive pursuit-like behavior in mice.
Brain research
Apr 8, 2025
Predator-prey interactions exemplify adaptive intelligence refined by evolution, yet replicating these behaviors in artificial systems remains challenging. Here, we introduce PursuitNet, a deep learning framework specifically designed to model the co...
Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals.
Cell
Apr 8, 2025
Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new or improved biosensors and microscopy technology. This creates major computational challenges to ex...
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