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Signal Peptides Generated by Attention-Based Neural Networks.

ACS synthetic biology
Short (15-30 residue) chains of amino acids at the amino termini of expressed proteins known as signal peptides (SPs) specify secretion in living cells. We trained an attention-based neural network, the Transformer model, on data from all available o...

Inexpensive, non-invasive biomarkers predict Alzheimer transition using machine learning analysis of the Alzheimer's Disease Neuroimaging (ADNI) database.

PloS one
The Alzheimer's Disease Neuroimaging (ADNI) database is an expansive undertaking by government, academia, and industry to pool resources and data on subjects at various stage of symptomatic severity due to Alzheimer's disease. As expected, magnetic r...

Supervised machine learning for the early prediction of acute respiratory distress syndrome (ARDS).

Journal of critical care
PURPOSE: Acute respiratory distress syndrome (ARDS) is a serious respiratory condition with high mortality and associated morbidity. The objective of this study is to develop and evaluate a novel application of gradient boosted tree models trained on...

The effect of deep convolutional neural networks on radiologists' performance in the detection of hip fractures on digital pelvic radiographs.

European journal of radiology
PURPOSE: The purpose of our study is to develop deep convolutional neural network (DCNN) for detecting hip fractures using CT and MRI as a gold standard, and to evaluate the diagnostic performance of 7 readers with and without DCNN.

Using intravascular ultrasound image-based fluid-structure interaction models and machine learning methods to predict human coronary plaque vulnerability change.

Computer methods in biomechanics and biomedical engineering
Plaque vulnerability prediction is of great importance in cardiovascular research. In vivo follow-up intravascular ultrasound (IVUS) coronary plaque data were acquired from nine patients to construct fluid-structure interaction models to obtain plaqu...

A machine learning approach for mortality prediction only using non-invasive parameters.

Medical & biological engineering & computing
At present, the traditional scoring methods generally utilize laboratory measurements to predict mortality. It results in difficulties of early mortality prediction in the rural areas lack of professional laboratorians and medical laboratory equipmen...

Early detection of type 2 diabetes mellitus using machine learning-based prediction models.

Scientific reports
Most screening tests for T2DM in use today were developed using multivariate regression methods that are often further simplified to allow transformation into a scoring formula. The increasing volume of electronically collected data opened the opport...