AIMC Topic: Autophagy

Clear Filters Showing 31 to 34 of 34 articles

Autophagy and Apoptosis Specific Knowledgebases-guided Systems Pharmacology Drug Research.

Current cancer drug targets Jan 1, 2019
BACKGROUND: Autophagy and apoptosis are the basic physiological processes in cells that clean up aged and mutant cellular components or even the entire cells. Both autophagy and apoptosis are disrupted in most major diseases such as cancer and neurol...
Signal Transduction Drug Development Antineoplastic Agents Computational Biology Knowledge Bases Protein Interaction Mapping Apoptosis Autophagy Humans Neoplasms Molecular Docking Simulation
View on PubMed DOI

[Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and the underlying mechanisms].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Nov 28, 2018
To investigate the effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells.
 Methods: First, A549 cells were divided into a control group and a low, medium or high dose of Brucea javan...
Carcinoma, Non-Small-Cell Lung Brucea Autophagy Cell Movement Lung Neoplasms Cell Proliferation Plant Oils Humans A549 Cells
View on PubMed DOI

[Y-27632 protects H9c2 cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy pathway].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Nov 1, 2017
Objective To investigate the protective effect of preconditioning with Rho-kinase inhibitor Y-27632 on H9c2 cardiomyocytes against hypoxia/reoxygenation (H/R) injury, and explore its underlying mechanism. Methods H9c2 cardiomyocytes were divided into...
Amides Phosphorylation Oxygen Autophagy Protective Agents Animals Pyridines Cell Hypoxia Apoptosis Cell Survival Myosin Light Chains Cell Line Myocytes, Cardiac Rats Beclin-1 Signal Transduction L-Lactate Dehydrogenase
View on PubMed

Astragalus Polysaccharide Inhibits Autophagy and Apoptosis from Peroxide-Induced Injury in C2C12 Myoblasts.

Cell biochemistry and biophysics Nov 1, 2015
The aim is to study the effects and underlying mechanisms of astragalus polysaccharide (APS) on the peroxide-induced injury in C2C12 myoblasts in vitro. Cell viability in the presence or absence of APS was detected by the methyl thiazolyl tetrazolium...
TOR Serine-Threonine Kinases bcl-2-Associated X Protein Autophagy Myoblasts Microscopy, Electron Polysaccharides Proto-Oncogene Proteins c-bcl-2 Cell Line Ribosomal Protein S6 Kinases, 70-kDa Cell Survival Caspase 3 Blotting, Western Astragalus Plant Signal Transduction Cytochromes c Apoptosis Mice Microtubule-Associated Proteins Animals Hydrogen Peroxide
View on PubMed DOI
Popular Topics
Recent Journals