AIMC Topic: Bacteria

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Optimizing phage therapy with artificial intelligence: a perspective.

Frontiers in cellular and infection microbiology
Phage therapy is emerging as a promising strategy against the growing threat of antimicrobial resistance, yet phage and bacteria are incredibly diverse and idiosyncratic in their interactions with one another. Clinical applications of phage therapy o...

Risk-reward trade-off during carbon starvation generates dichotomy in motility endurance among marine bacteria.

Nature microbiology
Copiotrophic marine bacteria contribute to the control of carbon storage in the ocean by remineralizing organic matter. Motility presents copiotrophs with a risk-reward trade-off: it is highly beneficial in seeking out sparse nutrient hotspots, but e...

TaxaCal: enhancing species-level profiling accuracy of 16S amplicon data.

BMC bioinformatics
BACKGROUND: 16S rRNA amplicon sequencing is a widely used method for microbiome composition analysis due to its cost-effectiveness and lower data requirements compared to metagenomic whole-genome sequencing (WGS). However, inherent limitations in 16S...

Synergistic potential of halophytes and halophilic/halotolerant plant growth-promoting bacteria in saline soil remediation: Adaptive mechanisms, challenges, and sustainable solutions.

Microbiological research
Salinity stress poses significant challenges to agriculture, reducing productivity and limiting arable land by causing ionic and osmotic imbalances in plants, disrupting physiological processes, and leading to soil degradation over time. Halophytes a...

Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.

Gut microbes
Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). We analyzed microbiomes of obese children with and w...

Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

mBio
Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show that the gut microbiota influences and is influenced by anticancer drugs, data from patients paired with careful side effect monitoring remains limited....

Brassica microgreens shape gut microbiota and functional metabolite profiles in a species-related manner: A multi-omics approach following in vitro gastrointestinal digestion and large intestine fermentation.

Microbiological research
Brassicaceae microgreens constitute a novel and promising source of bioactive compounds, such as polyphenols and glucosinolates. In this work, an integrative computational approach was performed to decipher the interaction between bioaccessible micro...

Distinguishing critical microbial community shifts from normal temporal variability in human and environmental ecosystems.

Scientific reports
Differentiating significant microbial community changes from normal fluctuations is vital for understanding microbial dynamics in human and environmental ecosystems. This knowledge could enable early warning systems to monitor critical changes affect...

Fluorescence-based spectrometric and imaging methods and machine learning analyses for microbiota analysis.

Mikrochimica acta
Most microbiota determination (skin, gut, soil, etc.) are currently conducted in a laboratory using expensive equipment and lengthy procedures, including culture-dependent methods, nucleic acid amplifications (including quantitative PCR), DNA microar...

Standardizing a microbiome pipeline for body fluid identification from complex crime scene stains.

Applied and environmental microbiology
Recent advances in next-generation sequencing have opened up new possibilities for applying the human microbiome in various fields, including forensics. Researchers have capitalized on the site-specific microbial communities found in different parts ...