Fluorescence enhancement using nanocavity structures is a promising approach for rapid detection of amphiphilic biomarkers, which are essential for diagnosing diseases such as cancer and infections. This paper presents the use of a silver nanocube (A...
Metabolic-associated fatty liver disease (MAFLD), a global health challenge linked to metabolic syndrome, requires accurate severity stratification for clinical management. Current invasive diagnostic methods limit practical implementation. This stud...
Translational research : the journal of laboratory and clinical medicine
Jul 1, 2025
Acute Respiratory Distress Syndrome (ARDS), characterized by the rapid onset of respiratory failure and mortality rates of ∼40%, remains a significant challenge in critical care medicine. Despite advances in supportive care, accurate prediction of AR...
Rapid changes in dietary patterns have led to a rise in cardiometabolic diseases (CMDs) worldwide, highlighting the urgent need for effective dietary strategies to address the health issues. Compared to Caucasians, Asians are more susceptible to CMDs...
Expert review of molecular diagnostics
Jul 1, 2025
INTRODUCTION: Accurate prediction of short-term mortality is crucial for optimizing clinical prognosis and providing treatment decisions. Conventional metrics, including physiological indicators, laboratory indexes and scoring systems, suffer from li...
Lactate metabolism is implicated in myocardial infarction (MI), yet the underlying mechanisms are not fully understood. Identifying lactate metabolism-related genes (LMRGs) could uncover new diagnostic and therapeutic targets for MI. We conducted a b...
New psychoactive substances (NPS) pose an increasing challenge for clinical and forensic toxicology due to the initial lack of analytical and metabolic data. This study evaluates the performance of four in silico prediction tools (GLORYx, BioTransfor...
Neuroscience and biobehavioral reviews
Jul 1, 2025
Traditional diagnostic methods for major depressive disorder (MDD), which rely on subjective assessments, may compromise diagnostic accuracy. In contrast, machine learning models have the potential to classify and diagnose MDD more effectively, reduc...
Background: Sepsis-associated acute kidney injury (SA-AKI) is a life-threatening complication with mortality rates exceeding 50%, yet its molecular drivers remain poorly defined. Dysregulated coagulation is increasingly implicated in SA-AKI pathogene...
International journal of medical informatics
Jul 1, 2025
BACKGROUND: Machine learning algorithms (MLA) gained prominence in nutritional epidemiology for analyzing dietary associations and uncovering intricate patterns within data. We explored dietary patterns associated with serum iron biomarkers and vitam...
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