AIMC Topic: Biosensing Techniques

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Artificial intelligence enhanced electrochemical immunoassay for staphylococcal enterotoxin B.

Scientific reports
Staphylococcal enterotoxin B (SEB) holds critical importance in disease diagnosis, food safety, and public health due to its high toxicity and potent pathogenicity. Traditional immunoassay methods for detecting SEB often exhibit insufficient accuracy...

Machine learning-powered activatable NIR-II fluorescent nanosensor for in vivo monitoring of plant stress responses.

Nature communications
Real-time monitoring of plant stress signaling molecules is crucial for early disease diagnosis and prevention. However, existing methods are often invasive and lack sensitivity, rendering them inadequate for continuous monitoring of subtle plant str...

Deciphering the history of ERK activity from fixed-cell immunofluorescence measurements.

Nature communications
The RAS/ERK pathway plays a central role in diagnosis and therapy for many cancers. ERK activity is highly dynamic within individual cells and drives cell proliferation, metabolism, and other processes through effector proteins including c-Myc, c-Fos...

Development of Non-Invasive Continuous Glucose Prediction Models Using Multi-Modal Wearable Sensors in Free-Living Conditions.

Sensors (Basel, Switzerland)
Continuous monitoring of glucose levels is important for diabetes management and prevention. While traditional glucose monitoring methods are often invasive and expensive, recent approaches using machine learning (ML) models have explored non-invasiv...

Single-Protein Determinations by Magnetofluorescent Qubit Imaging with Artificial-Intelligence Augmentation at the Point-Of-Care.

ACS nano
Conventional point-of-care testing (POCT) has limitations in sensitivity with high risks of missed detection or false positive, which restrains its applications for routine outpatient care analysis and early clinical diagnosis. By merits of the cutti...

Flexible iontronic sensing.

Chemical Society reviews
The emerging flexible iontronic sensing (FITS) technology has introduced a novel modality for tactile perception, mimicking the topological structure of human skin while providing a viable strategy for seamless integration with biological systems. Wi...

Advanced droplet microfluidic platform for high-throughput screening of industrial fungi.

Biosensors & bioelectronics
Industrial fungi are pivotal candidates for the production of a diverse array of bioproducts. To enhance their productivity, these strains are frequently subjected to genetic modifications. Following transformation, the selection of optimal productio...

Revolutionizing biosensing with wearable microneedle patches: innovations and applications.

Journal of materials chemistry. B
Wearable microneedle (MN) patches have emerged as a transformative platform for biosensing, offering a minimally invasive and user-friendly approach to real-time health monitoring and disease diagnosis. Primarily designed to access interstitial fluid...

Electrochemical microfluidic biosensors for the detection of cancer biomarker miRNAs.

Talanta
Cancer is a formidable adversary in contemporary healthcare. Routine screening and early diagnosis are crucial for favourable therapeutic outcomes. Publications, clinical trials, and patent landscape analysis suggest miRNA as promising biomarkers for...

Histidine-engineered Cu-BTC nanozyme with enhanced laccase-like activity combining the machine learning for precise recognition of Beta-lactam antibiotics.

Biosensors & bioelectronics
Although nanozyme sensor arrays can simultaneously recognize multiple target substances, they are currently rarely used for identifying Beta-lactam antibiotics (BLs). This may be due to the lower catalytic performance of some nanozymes in practical a...