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Brain Injuries

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A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury.

Brain injury
BACKGROUND: Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke, only a single study has evaluated VILIP-1 as a biomarker of traumatic brain injury (TBI). ...

A machine learning based approach for identifying traumatic brain injury patients for whom a head CT scan can be avoided.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Head CT scan is more often used to evaluate patients with suspected traumatic brain injury (TBI). However, the use of head CT scans in evaluating TBI is costly with low value endeavor. In this paper, we propose a new algorithm and a set of features t...

Adaptive hybrid robotic system for rehabilitation of reaching movement after a brain injury: a usability study.

Journal of neuroengineering and rehabilitation
BACKGROUND: Brain injury survivors often present upper-limb motor impairment affecting the execution of functional activities such as reaching. A currently active research line seeking to maximize upper-limb motor recovery after a brain injury, deals...

Dynamic functional network connectivity discriminates mild traumatic brain injury through machine learning.

NeuroImage. Clinical
Mild traumatic brain injury (mTBI) can result in symptoms that affect a person's cognitive and social abilities. Improvements in diagnostic methodologies are necessary given that current clinical techniques have limited accuracy and are solely based ...

Ankle passive and active movement training in children with acute brain injury using a wearable robot.

Journal of rehabilitation medicine
OBJECTIVE: To evaluate the feasibility and effectiveness of a wearable robotic device in guiding isometric torque generation and passive-active movement training for ankle motor recovery in children with acute brain injury.

Robotically-driven orthoses exert proximal-to-distal differential recovery on the lower limbs in children with hemiplegia, early after acquired brain injury.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Robotically-driven orthoses (RDO) are promising for treating gait impairment in children with hemiplegia after acquired brain injury (ABI). Despite this, existing literature on the employment of RDO in ABI is scanty, and cohorts' age spans throughout...

Robot-Guided Neuronavigated Repetitive Transcranial Magnetic Stimulation (rTMS) in Central Neuropathic Pain.

Archives of physical medicine and rehabilitation
OBJECTIVES: To confirm and extend previous results involving repetitive transcranial magnetic stimulation (rTMS) aimed at alleviating refractory central neuropathic pain (CNP). To evaluate pain relief in detail and to assess ongoing benefits after on...

Do powered over-ground lower limb robotic exoskeletons affect outcomes in the rehabilitation of people with acquired brain injury?

Disability and rehabilitation. Assistive technology
To assess the effects of lower limb robotic exoskeletons on outcomes in the rehabilitation of people with acquired brain injury. A systematic review of seven electronic databases was conducted. The primary outcome of interest was neuromuscular funct...

Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study.

Lancet (London, England)
BACKGROUND: Non-contrast head CT scan is the current standard for initial imaging of patients with head trauma or stroke symptoms. We aimed to develop and validate a set of deep learning algorithms for automated detection of the following key finding...