Clinical cancer research : an official journal of the American Association for Cancer Research
Jan 16, 2026
PURPOSE: Despite current standard-of-care endocrine therapy, distant recurrence remains a concern for patients with hormone receptor-positive (HR+)/HER2- early breast cancer (EBC). Understanding individual recurrence risk would aid in clinical decisi...
UNLABELLED: Preinvasive breast cancer, or ductal carcinoma in situ (DCIS), shares many morphologic and genomic features with invasive breast cancer, yet most DCIS tumors remain indolent over decades. In this study, we performed spatial analyses of so...
Randomized controlled trials (RCTs) have confirmed the mortality benefits of screening mammography and are the gold standard for evaluating new diagnostic tests and medical interventions. Reliable and rigorous execution of RCTs can be complex and req...
OBJECTIVE: The purpose of this study is to compare radiologists' breast cancer screening performance before and after the implementation of an artificial intelligence (AI) detection system for digital breast tomosynthesis (DBT).
INTRODUCTION: A new perspective on cancer metabolism suggests that it varies by context and is diverse. Cancer metabolism reprogramming can create a heterogeneous microenvironment that affects immune cell infiltration and function, complicating the s...
BACKGROUND: Malignant tumors are a major global health crisis, causing 25% of deaths in China, with lung, liver, thyroid, breast, and colon cancers being the most common. Understanding the factors influencing hospitalization costs for these cancers i...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 15, 2025
Breast cancer is one of the most common tumors in women, and early screening can significantly reduce mortality rates. Meanwhile, accurately identifying HER2-positive and HER2-negative subtypes of breast cancer is critical for helping doctors determi...
UNLABELLED: Recent studies have reported increases in early-onset cancer cases (diagnosed less than 50 years of age) and raised questions about whether the increase is related to earlier diagnosis from nonspecific medical tests as reflected by decrea...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Nov 10, 2025
PURPOSE: Shear wave elastography (SWE) has been investigated as a complement to B-mode ultrasound for breast cancer diagnosis. Although multicenter trials suggest benefits for patients with Breast Imaging Reporting and Data System (BI-RADS) 4(a) brea...
Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast cancer. Pro...
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