AIMC Topic: Carcinoma, Intraductal, Noninfiltrating
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Predicting Underestimation of Invasive Cancer in Patients with Core-Needle-Biopsy-Diagnosed Ductal Carcinoma In Situ Using Deep Learning Algorithms.
Tomography (Ann Arbor, Mich.)
Dec 20, 2022
The prediction of an occult invasive component in ductal carcinoma in situ (DCIS) before surgery is of clinical importance because the treatment strategies are different between pure DCIS without invasive component and upgraded DCIS. We demonstrated ...
A deep learning model for breast ductal carcinoma in situ classification in whole slide images.
Virchows Archiv : an international journal of pathology
Jan 25, 2022
The pathological differential diagnosis between breast ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) is of pivotal importance for determining optimum cancer treatment(s) and clinical outcomes. Since conventional diagnosis by pat...
Improving DCIS diagnosis and predictive outcome by applying artificial intelligence.
Biochimica et biophysica acta. Reviews on cancer
Apr 29, 2021
Breast ductal carcinoma in situ (DCIS) is a preinvasive lesion that is considered to be a precursor to invasive breast cancer. Nevertheless, not all DCIS will progress to invasion. Current histopathological classification systems are unable to predic...
Multi-magnification-based machine learning as an ancillary tool for the pathologic assessment of shaved margins for breast carcinoma lumpectomy specimens.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Apr 26, 2021
The surgical margin status of breast lumpectomy specimens for invasive carcinoma and ductal carcinoma in situ (DCIS) guides clinical decisions, as positive margins are associated with higher rates of local recurrence. The "cavity shave" method of mar...
Deep learning-based grading of ductal carcinoma in situ in breast histopathology images.
Laboratory investigation; a journal of technical methods and pathology
Feb 19, 2021
Ductal carcinoma in situ (DCIS) is a non-invasive breast cancer that can progress into invasive ductal carcinoma (IDC). Studies suggest DCIS is often overtreated since a considerable part of DCIS lesions may never progress into IDC. Lower grade lesio...
Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation.
PLoS medicine
Aug 14, 2020
BACKGROUND: Prostate cancer (PC) is the most frequently diagnosed cancer in North American men. Pathologists are in critical need of accurate biomarkers to characterize PC, particularly to confirm the presence of intraductal carcinoma of the prostate...
Prospective Analysis Using a Novel CNN Algorithm to Distinguish Atypical Ductal Hyperplasia From Ductal Carcinoma in Situ in Breast.
Clinical breast cancer
Jun 7, 2020
INTRODUCTION: We previously developed a convolutional neural networks (CNN)-based algorithm to distinguish atypical ductal hyperplasia (ADH) from ductal carcinoma in situ (DCIS) using a mammographic dataset. The purpose of this study is to further va...
Identification and transfer of spatial transcriptomics signatures for cancer diagnosis.
Breast cancer research : BCR
Jan 13, 2020
BACKGROUND: Distinguishing ductal carcinoma in situ (DCIS) from invasive ductal carcinoma (IDC) regions in clinical biopsies constitutes a diagnostic challenge. Spatial transcriptomics (ST) is an in situ capturing method, which allows quantification ...
Assessment of Machine Learning of Breast Pathology Structures for Automated Differentiation of Breast Cancer and High-Risk Proliferative Lesions.
JAMA network open
Aug 2, 2019
IMPORTANCE: Following recent US Food and Drug Administration approval, adoption of whole slide imaging in clinical settings may be imminent, and diagnostic accuracy, particularly among challenging breast biopsy specimens, may benefit from computerize...
A whole slide image-based machine learning approach to predict ductal carcinoma in situ (DCIS) recurrence risk.
Breast cancer research : BCR
Jul 29, 2019
BACKGROUND: Breast ductal carcinoma in situ (DCIS) represent approximately 20% of screen-detected breast cancers. The overall risk for DCIS patients treated with breast-conserving surgery stems almost exclusively from local recurrence. Although a mas...
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