AIMC Topic: Case-Control Studies

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Causes of death in individuals with lifetime major depression: a comprehensive machine learning analysis from a community-based autopsy center.

BMC psychiatry
BACKGROUND: Depression can be associated with increased mortality and morbidity, but no studies have investigated the specific causes of death based on autopsy reports. Autopsy studies can yield valuable and detailed information on pathological ailme...

Machine learning-enhanced HRCT analysis for diagnosis and severity assessment in pediatric asthma.

Pediatric pulmonology
OBJECTIVES: Chest high-resolution computed tomography (HRCT) is conditionally recommended to rule out conditions that mimic or coexist with severe asthma in children. However, it may provide valuable insights into identifying structural airway change...

Plasma-based near-infrared spectroscopy for early diagnosis of lung cancer.

Journal of pharmaceutical and biomedical analysis
Lung cancer (LC) continues to be a leading death cause in China, primarily due to late diagnosis. This study aimed to evaluate the effectiveness of using plasma-based near-infrared spectroscopy (NIRS) for LC early diagnosis. A total of 171 plasma sam...

Self-organizing maps for exploration and classification of nuclear magnetic resonance spectra for untargeted metabolomics of breast cancer.

Journal of pharmaceutical and biomedical analysis
Metabolomics has emerged as a powerful tool for identifying biomarkers of disease, and nuclear magnetic resonance (NMR) spectroscopy allows for the simultaneous detection of a wide range of metabolites. However, due to complex interactions within met...

Detecting outliers in case-control cohorts for improving deep learning networks on Schizophrenia prediction.

Journal of integrative bioinformatics
This study delves into the intricate genetic and clinical aspects of Schizophrenia, a complex mental disorder with uncertain etiology. Deep Learning (DL) holds promise for analyzing large genomic datasets to uncover new risk factors. However, based o...

Speech-based recognition and estimating severity of PTSD using machine learning.

Journal of affective disorders
BACKGROUND: Traditional methodologies for diagnosing post-traumatic stress disorder (PTSD) primarily rely on interviews, incurring considerable costs and lacking objective indices. Integrating biomarkers and machine learning techniques into this diag...

Predictive modeling of lower extreme deep vein thrombosis following radical gastrectomy for gastric cancer: based on multiple machine learning methods.

Scientific reports
Postoperative venous thromboembolic events (VTEs), such as lower extremity deep vein thrombosis (DVT), are major risk factors for gastric cancer (GC) patients following radical gastrectomy. Accurately predicting and managing these risks is crucial fo...

Comprehensive assessment of machine learning methods for diagnosing gastrointestinal diseases through whole metagenome sequencing data.

Gut microbes
The gut microbiome, linked significantly to host diseases, offers potential for disease diagnosis through machine learning (ML) pipelines. These pipelines, crucial in modeling diseases using high-dimensional microbiome data, involve selecting profile...

Plasma immune profiling combined with machine learning contributes to diagnosis and prognosis of active pulmonary tuberculosis.

Emerging microbes & infections
Tuberculosis (TB) remains one of the deadliest chronic infectious diseases globally. Early diagnosis not only prevents the spread of TB but also ensures effective treatment. However, the absence of non-sputum-based diagnostic tests often leads to del...