AIMC Topic: Chemotherapy, Adjuvant

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Cancer adjuvant chemotherapy strategic classification by artificial neural network with gene expression data: An example for non-small cell lung cancer.

Journal of biomedical informatics May 18, 2015
PURPOSE: Adjuvant chemotherapy (ACT) is used after surgery to prevent recurrence or metastases. However, ACT for non-small cell lung cancer (NSCLC) is still controversial. This study aimed to develop prediction models to distinguish who is suitable f...
Chemotherapy, Adjuvant Reproducibility of Results Humans Carcinoma, Non-Small-Cell Lung Neural Networks, Computer Lung Neoplasms Aged Neoplasm Recurrence, Local Computational Biology Male Machine Learning Neoplasm Metastasis Middle Aged Gene Expression Regulation, Neoplastic Algorithms Proportional Hazards Models Gene Expression Profiling Treatment Outcome Prognosis Kaplan-Meier Estimate Female
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Machine learning prediction of pathological complete response to neoadjuvant chemotherapy with peritumoral breast tumor ultrasound radiomics: compare with intratumoral radiomics and clinicopathologic predictors.

Breast cancer research and treatment Jul 1, 2025
PURPOSE: Noninvasive, accurate and novel approaches to predict patients who will achieve pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) could assist treatment strategies. The aim of this study was to explore the application...
Humans Machine Learning Prognosis Antineoplastic Combined Chemotherapy Protocols Female Treatment Outcome Adult Aged Neoadjuvant Therapy Breast Neoplasms Ultrasonography, Mammary Radiomics Chemotherapy, Adjuvant Middle Aged ROC Curve
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MRI-based multimodal AI model enables prediction of recurrence risk and adjuvant therapy in breast cancer.

Pharmacological research Jun 1, 2025
Timely intervention and improved prognosis for breast cancer patients rely on early metastasis risk detection and accurate treatment predictions. This study introduces an advanced multimodal MRI and AI-driven 3D deep learning model, termed the 3D-MMR...
Risk Assessment Aged Neoplasm Recurrence, Local Humans Deep Learning Adult Disease-Free Survival Magnetic Resonance Imaging Prognosis Breast Neoplasms Chemotherapy, Adjuvant Multimodal Imaging Retrospective Studies Tumor Microenvironment Female Middle Aged
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Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers-Based Model.

Cancer medicine Dec 1, 2024
BACKGROUND: Morphological and vascular characteristics of breast cancer can change during neoadjuvant chemotherapy (NAC). Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)-acquired pre- and mid-treatment quantitatively capture informatio...
Treatment Outcome Neoadjuvant Therapy Magnetic Resonance Imaging Chemotherapy, Adjuvant Humans Female Aged Adult Breast Neoplasms Middle Aged Deep Learning
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Use of Deep Learning to Evaluate Tumor Microenvironmental Features for Prediction of Colon Cancer Recurrence.

Cancer research communications May 23, 2024
UNLABELLED: Deep learning may detect biologically important signals embedded in tumor morphologic features that confer distinct prognoses. Tumor morphologic features were quantified to enhance patient risk stratification within DNA mismatch repair (M...
Humans Prognosis Female Aged Tumor Microenvironment Organoplatinum Compounds Leucovorin DNA Mismatch Repair Male Neoplasm Recurrence, Local Middle Aged Colonic Neoplasms Deep Learning Fluorouracil Antineoplastic Combined Chemotherapy Protocols Chemotherapy, Adjuvant
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Transforming breast cancer care: harnessing the power of artificial intelligence and imaging for predicting pathological complete response. a narrative review.

JPMA. The Journal of the Pakistan Medical Association Apr 1, 2024
This narrative review explores the transformative potential of Artificial Intelligence (AI) and advanced imaging techniques in predicting Pathological Complete Response (pCR) in Breast Cancer (BC) patients undergoing Neo-Adjuvant Chemotherapy (NACT)....
Humans Artificial Intelligence Female Breast Neoplasms Deep Learning Neoadjuvant Therapy Chemotherapy, Adjuvant
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Development and Validation of a Deep Learning CT Signature to Predict Survival and Chemotherapy Benefit in Gastric Cancer: A Multicenter, Retrospective Study.

Annals of surgery Dec 1, 2021
OBJECTIVE: We aimed to develop a deep learning-based signature to predict prognosis and benefit from adjuvant chemotherapy using preoperative computed tomography (CT) images.
Disease-Free Survival Chemotherapy, Adjuvant Deep Learning Nomograms Predictive Value of Tests Neoplasm Staging Humans Prognosis Retrospective Studies Tomography, X-Ray Computed Female Aged Stomach Neoplasms Male Middle Aged
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Radiographical assessment of tumour stroma and treatment outcomes using deep learning: a retrospective, multicohort study.

The Lancet. Digital health Jun 1, 2021
BACKGROUND: The tumour stroma microenvironment plays an important part in disease progression and its composition can influence treatment response and outcomes. Histological evaluation of tumour stroma is limited by access to tissue, spatial heteroge...
Progression-Free Survival Disease-Free Survival Proportional Hazards Models Stomach Chemotherapy, Adjuvant Prognosis ROC Curve Retrospective Studies Predictive Value of Tests Tomography, X-Ray Computed Area Under Curve Biomarkers, Tumor Humans Female Radiography Stomach Neoplasms Male Neural Networks, Computer Middle Aged Deep Learning China
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Setting guidelines to report the use of AI in clinical trials.

Nature medicine Sep 1, 2020
Breast Neoplasms Clinical Trials as Topic Chemotherapy, Adjuvant Humans Artificial Intelligence Female
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Impact of Machine Learning With Multiparametric Magnetic Resonance Imaging of the Breast for Early Prediction of Response to Neoadjuvant Chemotherapy and Survival Outcomes in Breast Cancer Patients.

Investigative radiology Feb 1, 2019
PURPOSE: The aim of this study was to assess the potential of machine learning with multiparametric magnetic resonance imaging (mpMRI) for the early prediction of pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and of survival ...
Middle Aged ROC Curve Treatment Outcome Neoadjuvant Therapy Magnetic Resonance Imaging Predictive Value of Tests Breast Survival Analysis Chemotherapy, Adjuvant Female Reproducibility of Results Aged Adult Breast Neoplasms Humans Machine Learning Prospective Studies Diffusion Magnetic Resonance Imaging
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