AIMC Topic: Carboplatin

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Shengxuebao Mixture improves carboplatin-induced anemia by inhibiting apoptosis and ferroptosis.

Journal of ethnopharmacology Apr 2, 2025
ETHNOPHARMACOLOGICAL RELEVANCE: Shengxuebao Mixture (SXB) is a traditional Chinese medicine which has been widely used on treating Chemotherapy-induced leukopenia and multiple anemia. It remains unclear whether SXB has a role in chemotherapeutic-indu...
Animals Male Antineoplastic Agents Drugs, Chinese Herbal Carboplatin Anemia Mice Apoptosis Ferroptosis
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Predicting response to immunotherapy plus chemotherapy in patients with esophageal squamous cell carcinoma using non-invasive Radiomic biomarkers.

BMC cancer Oct 30, 2021
OBJECTIVES: To develop and validate a radiomics model for evaluating treatment response to immune-checkpoint inhibitor plus chemotherapy (ICI + CT) in patients with advanced esophageal squamous cell carcinoma (ESCC).
Treatment Outcome Antibodies, Monoclonal, Humanized Support Vector Machine Humans Immune Checkpoint Inhibitors Tomography, X-Ray Computed Nomograms Female Antineoplastic Combined Chemotherapy Protocols Carboplatin Biomarkers, Tumor Docetaxel Bias Male Esophageal Squamous Cell Carcinoma Esophageal Neoplasms Middle Aged Combined Modality Therapy
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Correlation of Serum Cystatin C with Glomerular Filtration Rate in Patients Receiving Platinum-Based Chemotherapy.

Analytical cellular pathology (Amsterdam) Dec 18, 2016
. Serum cystatin C seems to be an accurate marker of glomerular filtration rate (GFR) compared to serum creatinine. The aim of this work was to explore the possibility of using serum cystatin C instead of serum creatinine to early predict renal failu...
Renal Insufficiency Creatinine Cisplatin Carboplatin Glomerular Filtration Rate Cystatin C Adult Sensitivity and Specificity Male Middle Aged Neoplasms Antineoplastic Combined Chemotherapy Protocols Prognosis Humans Female Biomarkers Aged
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Efficacy according to blind independent central review: Post-hoc analyses from the phase III, randomized, multicenter, IPASS study of first-line gefitinib versus carboplatin/paclitaxel in Asian patients with EGFR mutation-positive advanced NSCLC.

Lung cancer (Amsterdam, Netherlands) Nov 30, 2016
OBJECTIVE: The Phase III, randomized, open-label IPASS study (NCT00322452) of first-line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) gefitinib versus carboplatin/paclitaxel for Asian patients with advanced non-small-cell lun...
Paclitaxel Disease-Free Survival Smoking ErbB Receptors Protein Kinase Inhibitors Aged Gefitinib Aged, 80 and over Mutation Male Asian People Carboplatin Humans Antineoplastic Combined Chemotherapy Protocols Randomized Controlled Trials as Topic Female Neoplasm Staging Adenocarcinoma Quinazolines Middle Aged Carcinoma, Non-Small-Cell Lung Antineoplastic Agents Lung Neoplasms
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Adjuvant Carboplatin Treatment in 115 Patients With Stage I Seminoma: Retrospective Multicenter Survey.

Clinical genitourinary cancer Dec 17, 2015
BACKGROUND: The administration of carboplatin AUC 7 has become a standard adjuvant option for patients undergoing orchiectomy for stage I seminoma, in alternative to radiotherapy on retroperitoneal lymphnodes or surveillance. The toxicity of AUC 7 ca...
Testicular Neoplasms Seminoma Dose-Response Relationship, Drug Middle Aged Antineoplastic Agents Treatment Outcome Italy Carboplatin Chemotherapy, Adjuvant Humans Retrospective Studies Young Adult Adult Male
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Efficacy and safety of carboplatin with nab-paclitaxel versus docetaxel in older patients with squamous non-small-cell lung cancer (CAPITAL): a randomised, multicentre, open-label, phase 3 trial.

The lancet. Healthy longevity Dec 1, 2021
BACKGROUND: In Japan, docetaxel, a cytotoxic monotherapy, is the standard drug administered to older patients with advanced non-small-cell lung cancer (NSCLC). Carboplatin plus nab-paclitaxel has shown a high objective response rate in patients with ...
Antineoplastic Combined Chemotherapy Protocols Paclitaxel Aged Humans Carcinoma, Non-Small-Cell Lung Carboplatin Aged, 80 and over Carcinoma, Squamous Cell Albumins Lung Neoplasms Docetaxel Leukopenia
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