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Cholesterol, LDL

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Comparing a novel machine learning method to the Friedewald formula and Martin-Hopkins equation for low-density lipoprotein estimation.

PloS one
BACKGROUND: Low-density lipoprotein cholesterol (LDL-C) is a target for cardiovascular prevention. Contemporary equations for LDL-C estimation have limited accuracy in certain scenarios (high triglycerides [TG], very low LDL-C).

Modelling disease risk for amyloid A (AA) amyloidosis in non-human primates using machine learning.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We applied machine learning to identify the best predictors of amyloidosis in rhesus macaques from availabl...

Deep neural network for estimating low density lipoprotein cholesterol.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: LDL cholesterol (LDL-C) has been mainly estimated using the Friedewald equation, and other equations have recently been developed to complement the Friedewald equation. The present study aims to employ a deep neural network (DNN) to impro...

Identifying patients with familial hypercholesterolemia using data mining methods in the Northern Great Plain region of Hungary.

Atherosclerosis
BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is one of the most frequent diseases with monogenic inheritance. Previous data indicated that the heterozygous form occurred in 1:250 people. Based on these reports, around 36,000-40,000 people ...

[The gender features of disorders of composition of lipids of blood serum in patients with chronic pathology of kidneys.].

Klinicheskaia laboratornaia diagnostika
The purpose of the study was to investigate gender features of abnormalities of blood serum lipid composition and their relationship with clinical and functional manifestations in patients with chronic kidney disease (CKD). The study covered patients...