Studies in health technology and informatics
Jun 6, 2022
Core outcome sets (COS) are necessary to ensure the systematic collection, metadata analysis and sharing the information across studies. However, development of an area-specific clinical research is costly and time consuming. ClinicalTrials.gov, as a...
Journal of the American Medical Informatics Association : JAMIA
Apr 13, 2022
OBJECTIVE: Evidence synthesis teams, physicians, policy makers, and patients and their families all have an interest in following the outcomes of clinical trials and would benefit from being able to evaluate both the results posted in trial registrie...
Journal of the American Medical Informatics Association : JAMIA
Jan 29, 2022
OBJECTIVE: To analyze gender bias in clinical trials, to design an algorithm that mitigates the effects of biases of gender representation on natural-language (NLP) systems trained on text drawn from clinical trials, and to evaluate its performance.
Studies in health technology and informatics
Jan 14, 2022
Processing unstructured clinical texts is often necessary to support certain tasks in biomedicine, such as matching patients to clinical trials. Among other methods, domain-specific language models have been built to utilize free-text information. Th...
Journal of the American Medical Informatics Association : JAMIA
Jul 30, 2021
OBJECTIVE: We introduce Medical evidence Dependency (MD)-informed attention, a novel neuro-symbolic model for understanding free-text clinical trial publications with generalizability and interpretability.
AIM: To discuss ethical issues related to a complex study (PROFID) involving the development of a new, partly artificial intelligence-based, prediction model to enable personalised decision-making about the implantation of an implantable cardioverter...
Academic medicine : journal of the Association of American Medical Colleges
Jul 1, 2021
Machine learning (ML) algorithms are powerful prediction tools with immense potential in the clinical setting. There are a number of existing clinical tools that use ML, and many more are in development. Physicians are important stakeholders in the h...
Advances in experimental medicine and biology
Jan 1, 2021
While clinical trials have evolved and improved over time, fundamental changes are needed to reflect the outcomes of great relevance to the institutions where they are performed, by integrating scientific rationale and society's movement to increase ...