BACKGROUND: Currently, there is a paucity of literature addressing personalized risk stratification using multimodal data in patients with symptomatic aortic stenosis and heart failure with preserved ejection fraction (HFpEF) following transcatheter ...
INTRODUCTION: There is currently no comprehensive Amyotrophic Lateral Sclerosis (ALS) patient database in Singapore comparable to those available in Europe and the United States. We established the Singapore ALS registry (SingALS) to draw meaningful ...
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome, resulting in inconsistent findings across studies. Identifying a core set of genes consistently involved in COPD pathogenesis, independent of patient variability, i...
BACKGROUND: Acute heart failure (AHF) has become a significant challenge in older people with hip fractures. Timely identification and assessment of preoperative AHF have become key factors in reducing surgical risks and improving outcomes.
BACKGROUND: Patients presenting to emergency departments (EDs) for mental health problems have an elevated short-term risk of repeat ED visits, subsequent hospitalization, and suicide.
INTRODUCTION: Sepsis is a life-threatening condition characterized by widespread inflammatory response syndrome in the body resulting from infection. Previous studies have demonstrated that some inflammatory factors or nutritional elements contribute...
BACKGROUND: Lymphovascular invasion (LVI) is a significant histopathological marker associated with poor prognosis in patients. However, there is a notable lack of reliable, non-invasive preoperative tools to predict LVI accurately.
BACKGROUND & OBJECTIVE: Alzheimer's Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, whether AD and epilepsy share pathophysiological changes remains poorly defined. In this study, we levera...
Exclusive breastfeeding (EBF) plays a crucial role in infant gut microbiome assembly and development. However, few studies have investigated the effects of EBF in restoring a perturbed microbiome. In this study, we applied whole metagenomic sequencin...
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