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Colorectal Neoplasms

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Application of an Automated Deep Learning Program to A Diagnostic Classification Model: Differentiating High-Risk Adenomas Among Colorectal Polyps 10 mm or Smaller.

Journal of digestive diseases
OBJECTIVE: This study aimed to develop a computer-aided diagnosis (CADx) model using an automated deep learning (DL) program to classify low- and high-risk adenomas among colorectal polyps ≤ 10 mm with standard white-light endoscopy.

Development and Multi-center validation of a machine learning Model for advanced colorectal neoplasms screening.

Computers in biology and medicine
BACKGROUND: In colorectal cancer (CRC) screening programs, accurately identifying individuals at high risk for advanced colorectal neoplasia (ACN) is essential as they require further colonoscopy, early intervention, and monitoring follow-up. This st...

Construction and validation of machine learning-based predictive model for colorectal polyp recurrence one year after endoscopic mucosal resection.

World journal of gastroenterology
BACKGROUND: Colorectal polyps are precancerous diseases of colorectal cancer. Early detection and resection of colorectal polyps can effectively reduce the mortality of colorectal cancer. Endoscopic mucosal resection (EMR) is a common polypectomy pro...

Automated classification of tertiary lymphoid structures in colorectal cancer using TLS-PAT artificial intelligence tool.

Scientific reports
Colorectal cancer (CRC) ranks as the third most common and second deadliest cancer worldwide. The immune system, particularly tertiary lymphoid structures (TLS), significantly influences CRC progression and prognosis. TLS maturation, especially in th...

A fusion model to predict the survival of colorectal cancer based on histopathological image and gene mutation.

Scientific reports
Colorectal cancer (CRC) is a prevalent gastrointestinal tumor worldwide with high morbidity and mortality. Predicting the survival of CRC patients not only enhances understanding of their life expectancies but also aids clinicians in making informed ...

Generating research hypotheses to overcome key challenges in the early diagnosis of colorectal cancer - Future application of AI.

Cancer letters
We intend to explore the capability of ChatGPT 4.0 in generating innovative research hypotheses to address key challenges in the early diagnosis of colorectal cancer (CRC). We asked ChatGPT to generate hypotheses focusing on three main challenges: im...

Utility of comprehensive genomic profiling combined with machine learning for prognostic stratification in stage II/III colorectal cancer after adjuvant chemotherapy.

International journal of clinical oncology
BACKGROUND AND PURPOSE: Accurate recurrence risk evaluation in patients with stage II and III colorectal cancer (CRC) remains difficult. Traditional histopathological methods frequently fall short in predicting outcomes after adjuvant chemotherapy. T...

Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer.

Journal of translational medicine
BACKGROUND: The presence of tumour-infiltrating lymphocytes (TILs) is a well-established prognostic biomarker across multiple cancer types, with higher TIL counts being associated with lower recurrence rates and improved patient survival. We aimed to...

Artificial intelligence and whole slide imaging, a new tool for the microsatellite instability prediction in colorectal cancer: Friend or foe?

Critical reviews in oncology/hematology
Colorectal cancer (CRC) is the third most common and second most deadly cancer worldwide. Despite advances in screening and treatment, CRC is heterogeneous and the response to therapy varies significantly, limiting personalized treatment options. Cer...

Development and validation of computer-aided detection for colorectal neoplasms using deep learning incorporated with computed tomography colonography.

BMC gastroenterology
OBJECTIVES: Computed tomography (CT) colonography is increasingly recognized as a valuable modality for diagnosing colorectal lesions, however, the interpretation workload remains challenging for physicians. Deep learning-based artificial intelligenc...