International journal of biological sciences
Sep 7, 2018
N-methyladenosine (mA) is a prevalent RNA methylation modification involved in several biological processes. Hundreds or thousands of mA sites identified from different species using high-throughput experiments provides a rich resource to construct ...
Journal of diabetes science and technology
Sep 5, 2018
In the future artificial intelligence (AI) will have the potential to improve outcomes diabetes care. With the creation of new sensors for physiological monitoring sensors and the introduction of smart insulin pens, novel data relationships based on ...
IEEE/ACM transactions on computational biology and bioinformatics
Sep 3, 2018
Genome-Wide Association Studies (GWAS) are used to identify statistically significant genetic variants in case-control studies. The main objective is to find single nucleotide polymorphisms (SNPs) that influence a particular phenotype (i.e., disease ...
IEEE/ACM transactions on computational biology and bioinformatics
Sep 3, 2018
Biomedical named entity recognition (Bio-NER) is an important preliminary step for many biomedical text mining tasks. The current mainstream methods for NER are based on the neural networks to avoid the complex hand-designed features derived from var...
In recent years DNA microarray technology, leading to the generation of high-volume biological data, has gained significant attention. To analyze this high volume gene-expression data, one such powerful tool is Clustering. For any clustering algorith...
The prediction of subcellular localization of an apoptosis protein is still a challenging task, and existing methods mainly based on protein primary sequences. In this study, we propose a novel model called MACC-PSSM by integrating Moran autocorrelat...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 31, 2018
Gapped k-mers frequency vectors (gkm-fv) has been presented for extracting sequence features. Coupled with support vector machine (gkm-SVM), gkm-fvs have been used to achieve effective sequence-based predictions. However, the huge computation of a la...
Functional enrichment analysis is a fundamental and challenging task in bioinformatics. Most of the current enrichment analysis approaches individually evaluate functional terms and often output a list of enriched terms with high similarity and redun...
International microbiology : the official journal of the Spanish Society for Microbiology
Aug 24, 2018
Shikimate dehydrogenase (HpSDH) (EC 1.1.1.25) is a key enzyme in the shikimate pathway of Helicobacter pylori (H. pylori), which catalyzes the NADPH-dependent reversible reduction of 3-dehydroshikimate to shikimate. Targeting HpSDH has been recognize...
Journal of computational biology : a journal of computational molecular cell biology
Aug 22, 2018
Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for tree/netw...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.