AIMC Topic: Coronary Artery Disease

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Leveraging pulse wave signal properties for coronary artery calcification screening in CKD patients.

Computers in biology and medicine Jun 6, 2025
BACKGROUND AND AIMS: Chronic kidney disease (CKD) patients are particularly susceptible to coronary atherosclerosis, which can be assessed using computed tomography (CT)-based coronary artery calcium (CAC) score. However, such a costly examination mi...
Humans Machine Learning Retrospective Studies Tomography, X-Ray Computed Renal Insufficiency, Chronic Pulse Wave Analysis Coronary Artery Disease Coronary Vessels Vascular Calcification Female Aged Adult Male Middle Aged
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Comparative analysis of machine learning models for coronary artery disease prediction with optimized feature selection.

International journal of cardiology May 31, 2025
BACKGROUND: Coronary artery disease (CAD) is a major global cause of death, necessitating early, accurate prediction for better management. Traditional diagnostics are often invasive, costly, and less accessible. Machine learning (ML) offers a non-in...
Middle Aged Predictive Value of Tests Coronary Artery Disease Humans Machine Learning Databases, Factual Female Aged Male
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Divergent Immune Pathways in Coronary Artery Disease and Aortic Stenosis: The Role of Chronic Inflammation and Senescence.

International journal of molecular sciences May 29, 2025
Coronary artery disease (CAD) remains a major cause of cardiovascular morbidity and mortality, with growing evidence linking immune dysregulation to its pathogenesis. Aortic stenosis often coexists with CAD (ASCAD), representing an advanced disease f...
Aortic Valve Stenosis Coronary Artery Disease Immunosenescence Female Aged Male Middle Aged Inflammation Humans Cytokines Biomarkers
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Two birds with one stone: pre-TAVI coronary CT angiography combined with FFR helps screen for coronary stenosis.

BMC medical imaging May 26, 2025
OBJECTIVES: Since coronary artery disease (CAD) is a common comorbidity in patients with aortic valve stenosis, invasive coronary angiography (ICA) can be avoided if significant CAD can be screened with the non-invasive coronary CT angiography (cCTA)...
Transcatheter Aortic Valve Replacement Sensitivity and Specificity Male Aortic Valve Stenosis Machine Learning Predictive Value of Tests Coronary Angiography Retrospective Studies Humans Female Coronary Artery Disease Aged Computed Tomography Angiography Aged, 80 and over Coronary Stenosis Fractional Flow Reserve, Myocardial
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Direct evaluation of antiplatelet therapy in coronary artery disease by comprehensive image-based profiling of circulating platelets.

Nature communications May 15, 2025
Coronary artery disease (CAD) is a leading cause of death globally. Antiplatelet therapy remains crucial in preventing and treating CAD-associated thrombotic complications, but it concurrently amplifies the risk of bleeding. Unfortunately, traditiona...
Humans Female Aged Male Middle Aged Deep Learning Coronary Artery Disease Acute Coronary Syndrome Blood Platelets Platelet Aggregation Inhibitors Platelet Aggregation
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Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.

Journal of translational medicine May 9, 2025
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
Cell Hypoxia Male Humans Myocytes, Smooth Muscle Middle Aged Biomarkers Case-Control Studies Guanine Nucleotide Exchange Factors Female ROC Curve Foam Cells Aged Coronary Artery Disease
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Fast and automatic coronary artery segmentation using nnU-Net for non-contrast enhanced magnetic resonance coronary angiography.

The international journal of cardiovascular imaging Apr 26, 2025
Non-contrast enhanced magnetic resonance coronary angiography (MRCA) is a promising coronary heart disease screening modality. However, its clinical application is hindered by inherent limitations, including low spatial resolution and insufficient co...
Female Reproducibility of Results Aged Male Middle Aged Humans Coronary Artery Disease Image Interpretation, Computer-Assisted Observer Variation Automation Coronary Vessels Deep Learning Time Factors Predictive Value of Tests Coronary Angiography Magnetic Resonance Angiography Computed Tomography Angiography
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Optimising coronary imaging decisions with machine learning: an external validation study.

Open heart Apr 24, 2025
BACKGROUND: Exclusion of coronary stenosis in individuals with suggestive symptoms is challenging. Cardiac CT or coronary angiography is often used but is inefficient and costly and involves risks. Sex-stratified algorithms based on electronic health...
Middle Aged Predictive Value of Tests Humans Coronary Angiography Machine Learning Female Sex Factors Algorithms Coronary Vessels Retrospective Studies Coronary Artery Disease Computed Tomography Angiography Electronic Health Records Netherlands Coronary Stenosis Reproducibility of Results Aged Male
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Comparison of machine learning models with conventional statistical methods for prediction of percutaneous coronary intervention outcomes: a systematic review and meta-analysis.

BMC cardiovascular disorders Apr 23, 2025
INTRODUCTION: Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) models in predicting differ...
Coronary Artery Disease Risk Assessment Time Factors Treatment Outcome Predictive Value of Tests Humans Percutaneous Coronary Intervention Machine Learning Risk Factors Decision Support Techniques Aged Female Male Reproducibility of Results Middle Aged
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Plaque burden improves the detection of ischemic CAD over stenosis from coronary computed tomography angiography.

The international journal of cardiovascular imaging Apr 22, 2025
In symptomatic patients undergoing coronary CTA for suspected coronary artery disease (CAD), we assessed if quantification of plaque burden, in addition to luminal narrowing and clinical risk factors, offers incremental value for the identification o...
Coronary Stenosis Plaque, Atherosclerotic Vascular Calcification Computed Tomography Angiography Myocardial Perfusion Imaging Male Middle Aged Retrospective Studies Severity of Illness Index Female Predictive Value of Tests Reproducibility of Results Coronary Angiography Humans Risk Factors Radiographic Image Interpretation, Computer-Assisted Artificial Intelligence Aged Coronary Artery Disease Coronary Vessels Multidetector Computed Tomography
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