AIMC Topic: Deep Learning

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Optimizing stroke lesion segmentation: A dual-approach using Gaussian mixture models and nnU-Net.

Computers in biology and medicine
Machine learning-based stroke lesion segmentation models are widely used in biomedical imaging, but their ability to detect treatment effects remains largely unexplored. Gaussian Mixture Models (GMM) and nnU-Net are among the most prominent and well-...

Automatic ultrasound image alignment for diagnosis of pediatric distal forearm fractures.

International journal of computer assisted radiology and surgery
PURPOSE: The study aims to develop an automatic method to align ultrasound images of the distal forearm for diagnosing pediatric fractures. This approach seeks to bypass the reliance on X-rays for fracture diagnosis, thereby minimizing radiation expo...

Role and Potential of Artificial Intelligence in Biomarker Discovery and Development of Treatment Strategies for Amyotrophic Lateral Sclerosis.

International journal of molecular sciences
Neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), present significant challenges owing to their complex pathologies and a lack of curative treatments. Early detection and reliable biomarkers are critical but remain elusive. A...

Detecting the left atrial appendage in CT localizers using deep learning.

Scientific reports
Patients with cardioembolic stroke often undergo CT of the left atrial appendage (LAA), for example, to determine whether thrombi are present in the LAA. To guide the imaging process, technologists first perform a localizer scan, which is a prelimina...

Retraining and evaluation of machine learning and deep learning models for seizure classification from EEG data.

Scientific reports
Electroencephalography (EEG) is one of the most used techniques to perform diagnosis of epilepsy. However, manual annotation of seizures in EEG data is a major time-consuming step in the analysis process of EEGs. Different machine learning models hav...

A depression detection approach leveraging transfer learning with single-channel EEG.

Journal of neural engineering
Major depressive disorder (MDD) is a widespread mental disorder that affects health. Many methods combining electroencephalography (EEG) with machine learning or deep learning have been proposed to objectively distinguish between MDD and healthy indi...

Integrating genetic variation with deep learning provides context for variants impacting transcription factor binding during embryogenesis.

Genome research
Understanding how genetic variation impacts transcription factor (TF) binding remains a major challenge, limiting our ability to model disease-associated variants. Here, we used a highly controlled system of F crosses with extensive genetic diversity...

Deep Learning-Based Algorithm for Automatic Quantification of Nigrosome-1 and Parkinsonism Classification Using Susceptibility Map-Weighted MRI.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: The diagnostic performance of deep learning model that simultaneously detecting and quantifying nigrosome-1 abnormality by using susceptibility map-weighted imaging (SMwI) remains unexplored. This study aimed to develop and va...

Empowering Data Sharing in Neuroscience: A Deep Learning Deidentification Method for Pediatric Brain MRIs.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Privacy concerns, such as identifiable facial features within brain scans, have hindered the availability of pediatric neuroimaging data sets for research. Consequently, pediatric neuroscience research lags adult counterparts,...

Automated Quantification of Cerebral Microbleeds in SWI: Association with Vascular Risk Factors, White Matter Hyperintensity Burden, and Cognitive Function.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: The amount and distribution of cerebral microbleeds (CMB) are important risk factors for cognitive impairment. Our objective was to train and validate a deep learning (DL)-based segmentation model for cerebral microbleeds (CMB...