Blood-Brain-Barrier (BBB) is a strict permeability barrier for maintaining the Central Nervous System (CNS) homeostasis. One of the most important conditions to judge a CNS drug is to figure out whether it has BBB permeability or not. In the past 20 ...
Background Intratumor heterogeneity in lung cancer may influence outcomes. CT radiomics seeks to assess tumor features to provide detailed imaging features. However, CT radiomic features vary according to the reconstruction kernel used for image gene...
Background Computational models on the basis of deep neural networks are increasingly used to analyze health care data. However, the efficacy of traditional computational models in radiology is a matter of debate. Purpose To evaluate the accuracy and...
Event extraction and annotation has become a significant focus of recent efforts in biological text mining and information extraction (IE). However, event extraction, event annotation methods, and resources have so far focused almost exclusively on a...
Pre-harvest fruit yield estimation is useful to guide harvesting and marketing resourcing, but machine vision estimates based on a single view from each side of the tree ("dual-view") underestimates the fruit yield as fruit can be hidden from view. ...
IEEE journal of biomedical and health informatics
Jun 17, 2019
Many classical machine learning techniques have been used to explore Alzheimer's disease (AD), evolving from image decomposition techniques such as principal component analysis toward higher complexity, non-linear decomposition algorithms. With the a...
Computer methods and programs in biomedicine
Jun 17, 2019
BACKGROUND AND OBJECTIVE: The leading cause of vision loss in the Western World is Age-related Macular Degeneration (AMD), but together with modern medicines, tracking the number of Hyperreflective Foci (HF) on Optical Coherence Tomography (OCT) imag...
PURPOSE: The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods use only patient anatomy as input and assume consistent beam configuration for all ...
BACKGROUND: Protein secondary structure (PSS) is critical to further predict the tertiary structure, understand protein function and design drugs. However, experimental techniques of PSS are time consuming and expensive, and thus it's very urgent to ...
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