AIMC Topic: Diagnostic Tests, Routine

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Imaging of OA - From disease modification to clinical utility.

Best practice & research. Clinical rheumatology
Multiple disease-modifying osteoarthritis drug (DMOAD) trials were done in the last two decades, but no pharmacological agent has yet been approved by regulatory agencies as an effective therapy to date. Given the fact that we have seen the recent di...

UFO: A tool for unifying biomedical ontology-based semantic similarity calculation, enrichment analysis and visualization.

PloS one
BACKGROUND: Biomedical ontologies have been growing quickly and proven to be useful in many biomedical applications. Important applications of those data include estimating the functional similarity between ontology terms and between annotated biomed...

Digital microbiology.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
BACKGROUND: Digitalization and artificial intelligence have an important impact on the way microbiology laboratories will work in the near future. Opportunities and challenges lie ahead to digitalize the microbiological workflows. Making efficient us...

Detection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning Approaches.

International journal of molecular sciences
Flow cytometry nowadays is among the main working instruments in modern biology paving the way for clinics to provide early, quick, and reliable diagnostics of many blood-related diseases. The major problem for clinical applications is the detection ...

In vivo imaging of phosphocreatine with artificial neural networks.

Nature communications
Phosphocreatine (PCr) plays a vital role in neuron and myocyte energy homeostasis. Currently, there are no routine diagnostic tests to noninvasively map PCr distribution with clinically relevant spatial resolution and scan time. Here, we demonstrate ...

A new concordant partial AUC and partial c statistic for imbalanced data in the evaluation of machine learning algorithms.

BMC medical informatics and decision making
BACKGROUND: In classification and diagnostic testing, the receiver-operator characteristic (ROC) plot and the area under the ROC curve (AUC) describe how an adjustable threshold causes changes in two types of error: false positives and false negative...

The Big Picture on the "AI Turn" for Digital Health: The Internet of Things and Cyber-Physical Systems.

Omics : a journal of integrative biology
This article offers an analysis of the ways in which digital health innovations are being coproduced by mainstreaming of artificial intelligence (AI), the Internet of Things (IoT), and cyber-physical systems (CPS) in health care. CPS blurs the bounda...

Artificial intelligence-based decision-making for age-related macular degeneration.

Theranostics
Artificial intelligence (AI) based on convolutional neural networks (CNNs) has a great potential to enhance medical workflow and improve health care quality. Of particular interest is practical implementation of such AI-based software as a cloud-base...