AIMC Topic: Discriminant Analysis

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Discriminant analysis and machine learning approach for evaluating and improving the performance of immunohistochemical algorithms for COO classification of DLBCL.

Journal of translational medicine
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is classified into germinal center-like (GCB) and non-germinal center-like (non-GCB) cell-of-origin groups, entities driven by different oncogenic pathways with different clinical outcomes. DLBCL clas...

Detection of respiratory rate using a classifier of waves in the signal from a FBG-based vital signs sensor.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Monitoring of changes in respiratory rate provides information on a patient's psychophysical state. This paper presents a respiratory rate detection method based on analysis of signals from a fiber Bragg grating (FBG)-based ...

MLSeq: Machine learning interface for RNA-sequencing data.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data....

Deep Robust Framework for Protein Function Prediction Using Variable-Length Protein Sequences.

IEEE/ACM transactions on computational biology and bioinformatics
The order of amino acids in a protein sequence enables the protein to acquire a conformation suitable for performing functions, thereby motivating the need to analyze these sequences for predicting functions. Although machine learning based approache...

Application of Artificial Neural Networks to Identify Alzheimer's Disease Using Cerebral Perfusion SPECT Data.

International journal of environmental research and public health
The aim of this study was to demonstrate the usefulness of artificial neural networks in Alzheimer disease diagnosis (AD) using data of brain single photon emission computed tomography (SPECT). The results were compared with discriminant analysis. Th...

Statistical characterization and classification of colon microarray gene expression data using multiple machine learning paradigms.

Computer methods and programs in biomedicine
OBJECTIVE: A colon microarray data is a repository of thousands of gene expressions with different strengths for each cancer cell. It is necessary to detect which genes are responsible for cancer growth. This study presents an exhaustive comparative ...

Analysis of Machine Learning Algorithms for Diagnosis of Diffuse Lung Diseases.

Methods of information in medicine
UNLABELLED: Computational Intelligence Re-meets Medical Image Processing A Comparison of Some Nature-Inspired Optimization Metaheuristics Applied in Biomedical Image Registration BACKGROUND:  Diffuse lung diseases (DLDs) are a diverse group of pulmon...

Deep divergence-based approach to clustering.

Neural networks : the official journal of the International Neural Network Society
A promising direction in deep learning research consists in learning representations and simultaneously discovering cluster structure in unlabeled data by optimizing a discriminative loss function. As opposed to supervised deep learning, this line of...

Evaluating classification accuracy for modern learning approaches.

Statistics in medicine
Deep learning neural network models such as multilayer perceptron (MLP) and convolutional neural network (CNN) are novel and attractive artificial intelligence computing tools. However, evaluation of the performance of these methods is not readily av...

Diagnosis of early gastric cancer based on fluorescence hyperspectral imaging technology combined with partial-least-square discriminant analysis and support vector machine.

Journal of biophotonics
This study investigated the feasibility of using fluorescence hyperspectral imaging technology to diagnose of early-stage gastric cancer. Fluorescence spectral images of 76 patients who were pathologically diagnosed as non-atrophic gastritis, premali...