AIMC Topic: Disease Susceptibility
Clear Filters Showing 31 to 40 of 45 articles
Network-Based Disease Module Discovery by a Novel Seed Connector Algorithm with Pathobiological Implications.
Journal of molecular biology
May 20, 2018
Understanding the genetic basis of complex diseases is challenging. Prior work shows that disease-related proteins do not typically function in isolation. Rather, they often interact with each other to form a network module that underlies dysfunction...
Heterogeneity Analysis and Diagnosis of Complex Diseases Based on Deep Learning Method.
Scientific reports
Apr 18, 2018
Understanding genetic mechanism of complex diseases is a serious challenge. Existing methods often neglect the heterogeneity phenomenon of complex diseases, resulting in lack of power or low reproducibility. Addressing heterogeneity when detecting ep...
Identification of immune signatures predictive of clinical protection from malaria.
PLoS computational biology
Oct 24, 2017
Antibodies are thought to play an essential role in naturally acquired immunity to malaria. Prospective cohort studies have frequently shown how continuous exposure to the malaria parasite Plasmodium falciparum cause an accumulation of specific respo...
Recapitulation of Ayurveda constitution types by machine learning of phenotypic traits.
PloS one
Oct 5, 2017
In Ayurveda system of medicine individuals are classified into seven constitution types, "Prakriti", for assessing disease susceptibility and drug responsiveness. Prakriti evaluation involves clinical examination including questions about physiologic...
Artificial neural network-based exploration of gene-nutrient interactions in folate and xenobiotic metabolic pathways that modulate susceptibility to breast cancer.
Gene
Jan 16, 2016
In the current study, an artificial neural network (ANN)-based breast cancer prediction model was developed from the data of folate and xenobiotic pathway genetic polymorphisms along with the nutritional and demographic variables to investigate how m...
An efficiency analysis of high-order combinations of gene-gene interactions using multifactor-dimensionality reduction.
BMC genomics
Jul 1, 2015
BACKGROUND: Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between diseases and polymorphisms in humans. However, the astronomical number of high-order combinations mak...
Using text mining techniques to extract phenotypic information from the PhenoCHF corpus.
BMC medical informatics and decision making
Jun 15, 2015
BACKGROUND: Phenotypic information locked away in unstructured narrative text presents significant barriers to information accessibility, both for clinical practitioners and for computerised applications used for clinical research purposes. Text mini...
Improving human brucellosis susceptibility mapping using effective and simultaneously metaheuristic-based feature selection and hyperparameter tuning.
Acta tropica
Jul 1, 2025
Human Brucellosis, a neglected zoonotic disease, affects 1.6 to 2.1 million people globally each year. In Iran, it has become a significant health concern, with an average annual incidence rate of 19.91 cases per 100,000 people. This study aims to cr...
Systems Human Immunology and AI: Immune Setpoint and Immune Health.
Annual review of immunology
Apr 1, 2025
The immune system, critical for human health and implicated in many diseases, defends against pathogens, monitors physiological stress, and maintains tissue and organismal homeostasis. It exhibits substantial variability both within and across indivi...
Biomarker Identification for Preterm Birth Susceptibility: Vaginal Microbiome Meta-Analysis Using Systems Biology and Machine Learning Approaches.
American journal of reproductive immunology (New York, N.Y. : 1989)
Jul 1, 2024
PROBLEM: The vaginal microbiome has a substantial role in the occurrence of preterm birth (PTB), which contributes substantially to neonatal mortality worldwide. However, current bioinformatics approaches mostly concentrate on the taxonomic classific...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 30978
- Neural Networks, Computer 29696
- Algorithms 26813
- Deep Learning 26324
- Artificial Intelligence 24267
- Robotics 13307
- Image Processing, Computer-Assisted 9512
- Retrospective Studies 9097
- Magnetic Resonance Imaging 6173
- Reproducibility of Results 5589
- Tomography, X-Ray Computed 4765
- Support Vector Machine 4678
- Computational Biology 4229
- Brain 4045
- Computer Simulation 3877
Recent Journals
- Scientific reports 5865
- Sensors (Basel, Switzerland) 4794
- PloS one 4011
- Neural networks : the official journal of the International Neural Network Society 2928
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1839
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1129
- Journal of chemical information and modeling 994
- Nature communications 938
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 850
- IEEE transactions on neural networks and learning systems 823