AIMC Topic: Drug Delivery Systems
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Miniature Robots for Battling Bacterial Infection.
ACS nano
Nov 11, 2024
Micro/nanorobots have shown great promise for minimally invasive bacterial infection therapy. However, bacterial infections usually form biofilms inside the body by aggregation and adhesion, preventing antibiotic penetration and increasing the likeli...
Leveraging machine learning to streamline the development of liposomal drug delivery systems.
Journal of controlled release : official journal of the Controlled Release Society
Nov 8, 2024
Drug delivery systems efficiently and safely administer therapeutic agents to specific body sites. Liposomes, spherical vesicles made of phospholipid bilayers, have become a powerful tool in this field, especially with the rise of microfluidic manufa...
Utilizing machine learning and molecular dynamics for enhanced drug delivery in nanoparticle systems.
Scientific reports
Nov 4, 2024
Materials data science and machine learning (ML) are pivotal in advancing cancer treatment strategies beyond traditional methods like chemotherapy. Nanotherapeutics, which merge nanotechnology with targeted drug delivery, exemplify this advancement b...
PREPRINT Machine Learning for the Sensitivity Analysis of a Model of the Cellular Uptake of Nanoparticles for the Treatment of Cancer.
International journal for numerical methods in biomedical engineering
Oct 29, 2024
Experimental studies on the cellular uptake of nanoparticles (NPs), useful for the investigation of NP-based drug delivery systems, are often difficult to interpret due to the large number of parameters that can contribute to the phenomenon. It is th...
Biohybrid Micro/Nanorobots: Pioneering the Next Generation of Medical Technology.
Advanced healthcare materials
Oct 7, 2024
Biohybrid micro/nanorobots hold a great potential for advancing biomedical research. These tiny structures, designed to mimic biological organisms, offer a promising method for targeted drug delivery, tissue engineering, biosensing/imaging, and cance...
Machine learning- a new paradigm in nanoparticle-mediated drug delivery to cancerous tissues through the human cardiovascular system enhanced by magnetic field.
Scientific reports
Sep 27, 2024
Nanoparticle-mediated drug delivery offers a promising approach to targeted cancer therapy, leveraging the ability of nanoparticles to deliver therapeutic agents directly to cancerous tissues with minimal impact on surrounding healthy cells. The pres...
Magnetically Actuated Soft Microrobot with Environmental Adaptative Multimodal Locomotion Towards Targeted Delivery.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sep 24, 2024
The development of environmentally adaptive solutions for magnetically actuated microrobots to enable targeted delivery in complex and confined fluid environments presents a significant challenge. Inspired by the natural locomotion of crucian carp, a...
Transitioning the production of lipidic mesophase-based delivery systems from lab-scale to robust industrial manufacturing following a risk-based quality by design approach augmented by artificial intelligence.
Journal of colloid and interface science
Sep 12, 2024
Lipidic mesophase drug carriers have demonstrated the capacity to host and effectively deliver a wide range of active pharmaceutical ingredients, yet they have not been as extensively commercialized as other lipid-based products, such as liposomal de...
Toward the Integration of Machine Learning and Molecular Modeling for Designing Drug Delivery Nanocarriers.
Advanced materials (Deerfield Beach, Fla.)
Sep 10, 2024
The pioneering work on liposomes in the 1960s and subsequent research in controlled drug release systems significantly advances the development of nanocarriers (NCs) for drug delivery. This field is evolved to include a diverse array of nanocarriers ...
Magnetic Miniature Soft Robot with Reprogrammable Drug-Dispensing Functionalities: Toward Advanced Targeted Combination Therapy.
Advanced materials (Deerfield Beach, Fla.)
Sep 9, 2024
Miniature robots are untethered actuators, which have great prospects to transform targeted drug delivery because they can potentially deliver high concentrations of medicine to the disease site(s) with minimal complications. However, existing miniat...
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