AIMC Topic: Drug Delivery Systems

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Emerging trends in NanoTheranostics: Integrating imaging and therapy for precision health care.

International journal of pharmaceutics
Nanotheranostics has garnered significant interest for its capacity to improve customized healthcare via targeted and efficient treatment alternatives. Nanotheranostics promises an innovative approach to precision medicine by integrating therapeutic ...

Navigating the future of oncology: the transformative role of microrobots in precision cancer therapy.

International journal of pharmaceutics
Systemic chemotherapy has long served as a cornerstone in the management of various malignancies. However, its inherent lack of specificity often leads to significant adverse effects, prompting the exploration of innovative nanomedicine strategies to...

Magnetic Control Strategies of Microrobot Swarm for Biomedical Applications.

ACS biomaterials science & engineering
Microrobot swarms have attracted significant attention in the biomedical field due to their small size, flexibility, powerful functionality, and ability to collaborate to achieve complex tasks. They show great potential in targeted drug delivery and ...

Novel design of 3D printed tumbling microrobots for in vivo targeted drug delivery.

Journal of controlled release : official journal of the Controlled Release Society
This paper presents innovative designs for 3D-printed tumbling microrobots, specifically engineered for targeted in vivo drug deliv- ery applications. The microrobot designs, created using stereolithography 3D printing technologies, incorporate perma...

Structural modification strategies for ferritin nanoparticles and their applications in biomedicine: a narrative review.

Nanoscale
Ferritin is an iron-storage protein that naturally self-assembles into a hollow spherical particle consisting of 24 identical subunits, and it serves a central role in iron metabolism. Ferritin's favorable drug-loading capacity, biocompatibility, int...

Hydrogel delivery systems in intervertebral disc degeneration: Current status and future perspectives.

Journal of controlled release : official journal of the Controlled Release Society
Intervertebral disc degeneration (IVDD) is a primary contributor to the development of low back pain, characterized by core pathological features which include extracellular matrix (ECM) degradation, oxidative stress, imbalanced inflammatory microenv...

Nebulized liposomal drug delivery: a SWOT analysis in drug development.

International journal of pharmaceutics
This critical review provided a detailed strengths, weaknesses, opportunities, and threats (SWOT) analysis of nebulized liposomal formulations, focusing on the strengths and translational potential. The formulations have notable strengths, such as en...

Development and application of an AI-empowered acoustic monitoring system for misuse detection in dry powder inhalers.

International journal of pharmaceutics
Misuse and poor inhalation techniques remain persistent issues in pulmonary drug delivery via dry powder inhalation. While acoustic-based monitoring has been a feasible strategy, existing approaches often depend on smartphones for signal collection, ...

Advanced biomaterials in immune modulation: The future of regenerative therapies.

International journal of pharmaceutics
Healing of tissue is a complex process controlled by immune responses in the forms of inflammatory, proliferative, and remodeling stages. Dysregulated immunity can interfere with healing and lead to fibrosis or chronic inflammation. Biomaterials engi...

Roadmap for Commercial Nanomedicine Development: Integrating Quality by Design Principles with Pharmaceutical Nanotechnology.

Molecular pharmaceutics
Integrating Quality by Design (QbD) principles into nanomedicine development marks a paradigm shift from traditional empirical approaches to more systematic risk-based strategies. This review explores the application of QbD in pharmaceutical nanotech...