Translation of the findings in basic science and clinical research into routine practice is hampered by large variations in human phenotype. Developments in genotyping and phenotyping, such as proteomics and lipidomics, are beginning to address these...
Rapid cell identification is achieved in a compact and field-portable system employing single random phase encoding to record opto-biological signatures of living biological cells of interest. The lensless, 3D-printed system uses a diffuser to encode...
Quantitative phase microscopy (QPM) is a label-free technique that enables monitoring of morphological changes at the subcellular level. The performance of the QPM system in terms of spatial sensitivity and resolution depends on the coherence propert...
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
33246838
Improving blood product quality and patient outcomes is an accepted goal in transfusion medicine research. Thus, there is an urgent need to understand the potential adverse effects on red blood cells (RBCs) during pre-transfusion storage. Current ass...
SIGNIFICANCE: Label-free quantitative phase imaging is a promising technique for the automatic detection of abnormal red blood cells (RBCs) in real time. Although deep-learning techniques can accurately detect abnormal RBCs from quantitative phase im...
Journal of the Optical Society of America. A, Optics, image science, and vision
33690460
In dual-wavelength interferometry, the key issue is how to efficiently retrieve the phases at each wavelength using the minimum number of wavelength-multiplexed interferograms. To address this problem, a new dual-wavelength interferogram decoupling m...
SIGNIFICANCE: Digital holographic microscopy (DHM) is a promising technique for the study of semitransparent biological specimen such as red blood cells (RBCs). It is important and meaningful to detect and count biological cells at the single cell le...
The investigation of cell shapes mostly relies on the manual classification of 2D images, causing a subjective and time consuming evaluation based on a portion of the cell surface. We present a dual-stage neural network architecture for analyzing fin...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
33891370
The Coulter principle is a widespread technique for sizing red blood cells (RBCs) in hematological analyzers. It is based on the monitoring of the electrical perturbations generated by cells passing through a micro-orifice, in which a concentrated el...
IEEE journal of biomedical and health informatics
33119516
Computer-assisted algorithms have become a mainstay of biomedical applications to improve accuracy and reproducibility of repetitive tasks like manual segmentation and annotation. We propose a novel pipeline for red blood cell detection and counting ...