AIMC Topic: Exosomes

Clear Filters Showing 41 to 46 of 46 articles

Accurate Diagnosis of Colorectal Cancer Using a Combination of Lectin-Induced Recombinase Polymerase Amplification and CRISPR/Cas12a Assay on a Point-of-Care Testing Platform with Deep Learning Assistant.

Analytical chemistry Jul 1, 2025
Specific glycosylation patterns on exosome surfaces represent novel diagnostic biomarkers for cancer liquid biopsy. Lectins can induce exosome aggregation through multiple bindings with exosomal glycoproteins. In this work, we developed a one-pot lec...
Colorectal Neoplasms CRISPR-Cas Systems Exosomes Bacterial Proteins Animals Endodeoxyribonucleases Lectins Nucleic Acid Amplification Techniques Recombinases Cell Line, Tumor Limit of Detection CRISPR-Associated Proteins Mice Point-of-Care Testing Deep Learning Humans
View on PubMed DOI

Machine learning-driven identification of exosome- related biomarkers in head and neck squamous cell carcinoma.

Frontiers in immunology Jan 1, 2025
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a common cancer associated with elevated mortality rates. Exosomes, diminutive extracellular vesicles, significantly contribute to tumour development, immunological evasion, and treatment r...
Humans Machine Learning Prognosis Gene Expression Profiling Computational Biology Gene Expression Regulation, Neoplastic Tumor Microenvironment Biomarkers, Tumor Databases, Genetic Exosomes Squamous Cell Carcinoma of Head and Neck Head and Neck Neoplasms
View on PubMed DOI

Machine learning-based analysis identifies and validates serum exosomal proteomic signatures for the diagnosis of colorectal cancer.

Cell reports. Medicine Aug 20, 2024
The potential of serum extracellular vesicles (EVs) as non-invasive biomarkers for diagnosing colorectal cancer (CRC) remains elusive. We employed an in-depth 4D-DIA proteomics and machine learning (ML) pipeline to identify key proteins, PF4 and AACT...
Proteome Exosomes Colorectal Neoplasms Biomarkers, Tumor Middle Aged Proteomics Male Machine Learning Female Aged Humans
View on PubMed DOI

Tri-modal liquid biopsy: Combinational analysis of circulating tumor cells, exosomes, and cell-free DNA using machine learning algorithm.

Clinical and translational medicine Aug 1, 2021
Cell-Free Nucleic Acids Circulating Tumor DNA Neoplastic Cells, Circulating Survival Analysis Liquid Biopsy Humans Machine Learning Exosomes
View on PubMed DOI

DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism.

Nucleic acids research May 7, 2021
Subcellular localization of messenger RNAs (mRNAs), as a prevalent mechanism, gives precise and efficient control for the translation process. There is mounting evidence for the important roles of this process in a variety of cellular events. Computa...
Exosomes Cell Nucleus Gene Ontology Ribosomes Humans Cell Membrane Neural Networks, Computer Proteomics Transcriptome Databases, Genetic Computational Biology Cytosol Databases, Protein Endoplasmic Reticulum RNA, Messenger Subcellular Fractions
View on PubMed DOI

Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Advances in experimental medicine and biology Jan 1, 2016
Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show ...
Microtubules Rats Signal Transduction Nerve Regeneration Schwann Cells Cell Communication Phenotype Biological Transport Ribosomes Axons Sural Nerve Exosomes Humans Animals Action Potentials Neural Networks, Computer RNA, Messenger
View on PubMed DOI
Popular Topics
Recent Journals