AIMC Topic: Fear

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Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times.

eLife
Dopamine (DA) neurons are to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulat...

On the boundary conditions of avoidance memory reconsolidation: An attractor network perspective.

Neural networks : the official journal of the International Neural Network Society
The reconsolidation and extinction of aversive memories and their boundary conditions have been extensively studied. Knowing their network mechanisms may lead to the development of better strategies for the treatment of fear and anxiety-related disor...

Identifying the presence and timing of discrete mood states prior to therapy.

Behaviour research and therapy
The present study tested a novel, person-specific method for identifying discrete mood profiles from time-series data, and examined the degree to which these profiles could be predicted by lagged mood and anxiety variables and time-based variables, i...

An Investigation of Various Machine and Deep Learning Techniques Applied in Automatic Fear Level Detection and Acrophobia Virtual Therapy.

Sensors (Basel, Switzerland)
In this paper, we investigate various machine learning classifiers used in our Virtual Reality (VR) system for treating acrophobia. The system automatically estimates fear level based on multimodal sensory data and a self-reported emotion assessment....

Multivoxel pattern analysis reveals dissociations between subjective fear and its physiological correlates.

Molecular psychiatry
In studies of anxiety and other affective disorders, objectively measured physiological responses have commonly been used as a proxy for measuring subjective experiences associated with pathology. However, this commonly adopted "biosignal" approach h...

Design and development of a robotic predator as a stimulus in conditioned place aversion for the study of the effect of ethanol and citalopram in zebrafish.

Behavioural brain research
Zebrafish are becoming a species of choice in psychopharmacology, laying a promising path to refined pharmacological manipulations and high-throughput behavioral phenotyping. The field of robotics has the potential to accelerate progress along this p...

Physiological indices of challenge and threat: A data-driven investigation of autonomic nervous system reactivity during an active coping stressor task.

Psychophysiology
We utilized a data-driven, unsupervised machine learning approach to examine patterns of peripheral physiological responses during a motivated performance context across two large, independent data sets, each with multiple peripheral physiological me...

Children's Fear and Pain During Medical Procedures: A Quality Improvement Study With a Humanoid Robot.

The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres
BACKGROUND: Pediatric patients undergo a variety of painful medical procedures.

Pain-Related Fear-Dissociable Neural Sources of Different Fear Constructs.

eNeuro
Fear of pain demonstrates significant prognostic value regarding the development of persistent musculoskeletal pain and disability. Its assessment often relies on self-report measures of pain-related fear by a variety of questionnaires. However, base...

Use of a robotic walking aid in rehabilitation to reduce fear of falling is feasible and acceptable from the end user's perspective: A randomised comparative study.

Maturitas
Objectives To determine the acceptability and feasibility of the use of a robotic walking aid to support the work of physiotherapists in reducing fear of falling in the rehabilitation of elderly patients with 'psychomotor disadaptation' (the most sev...