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Proteomic prediction of diverse incident diseases: a machine learning-guided biomarker discovery study using data from a prospective cohort study.

The Lancet. Digital health
BACKGROUND: Broad-capture proteomic technologies have the potential to improve disease prediction, enabling targeted prevention and management, but studies have so far been limited to very few selected diseases and have not evaluated predictive perfo...

Effects of vitamin D supplementation on a deep learning-based mammographic evaluation in SWOG S0812.

JNCI cancer spectrum
Deep learning-based mammographic evaluations could noninvasively assess response to breast cancer chemoprevention. We evaluated change in a convolutional neural network-based breast cancer risk model applied to mammograms among women enrolled in SWOG...

Deep Learning for Breast Cancer Risk Prediction: Application to a Large Representative UK Screening Cohort.

Radiology. Artificial intelligence
Purpose To develop an artificial intelligence (AI) deep learning tool capable of predicting future breast cancer risk from a current negative screening mammographic examination and to evaluate the model on data from the UK National Health Service Bre...

Physician and Artificial Intelligence Chatbot Responses to Cancer Questions From Social Media.

JAMA oncology
IMPORTANCE: Artificial intelligence (AI) chatbots pose the opportunity to draft template responses to patient questions. However, the ability of chatbots to generate responses based on domain-specific knowledge of cancer remains to be tested.

Improving Automated Hemorrhage Detection at Sparse-View CT via U-Net-based Artifact Reduction.

Radiology. Artificial intelligence
Purpose To explore the potential benefits of deep learning-based artifact reduction in sparse-view cranial CT scans and its impact on automated hemorrhage detection. Materials and Methods In this retrospective study, a U-Net was trained for artifact ...

Performance of an Open-Source Large Language Model in Extracting Information from Free-Text Radiology Reports.

Radiology. Artificial intelligence
Purpose To assess the performance of a local open-source large language model (LLM) in various information extraction tasks from real-life emergency brain MRI reports. Materials and Methods All consecutive emergency brain MRI reports written in 2022 ...

Impact of Transfer Learning Using Local Data on Performance of a Deep Learning Model for Screening Mammography.

Radiology. Artificial intelligence
Purpose To investigate the issues of generalizability and replication of deep learning models by assessing performance of a screening mammography deep learning system developed at New York University (NYU) on a local Australian dataset. Materials and...

A Machine Learning Algorithm Facilitates Prognosis Prediction and Treatment Selection for Barcelona Clinic Liver Cancer Stage C Hepatocellular Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Given its heterogeneity and diverse clinical outcomes, precise subclassification of Barcelona Clinic Liver Cancer stage C (BCLC-C) hepatocellular carcinoma (HCC) is required for appropriately determining patient prognosis and selecting treat...

A Comparison of Five Algorithmic Methods and Machine Learning Pattern Recognition for Artifact Detection in Electronic Records of Five Different Vital Signs: A Retrospective Analysis.

Anesthesiology
BACKGROUND: Research on electronic health record physiologic data is common, invariably including artifacts. Traditionally, these artifacts have been handled using simple filter techniques. The authors hypothesized that different artifact detection a...

Heterogeneous Effects of Continuous Positive Airway Pressure in Non-Sleepy Obstructive Sleep Apnea on Cardiovascular Disease Outcomes: Machine Learning Analysis of the ISAACC Trial (ECSACT Study).

Annals of the American Thoracic Society
Randomized controlled trials of continuous positive airway pressure (CPAP) therapy for cardiovascular disease (CVD) prevention among patients with obstructive sleep apnea (OSA) have been largely neutral. However, given that OSA is a heterogeneous di...