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Accurate Identification of Cancer Cells in Complex Pre-Clinical Models Using a Deep-Learning Neural Network: A Transfection-Free Approach.

Advanced biology
3D co-cultures are key tools for in vitro biomedical research as they recapitulate more closely the in vivo environment while allowing a tighter control on the culture's composition and experimental conditions. The limited technologies available for ...

Clinical artificial intelligence: teaching a large language model to generate recommendations that align with guidelines for the surgical management of GERD.

Surgical endoscopy
BACKGROUND: Large Language Models (LLMs) provide clinical guidance with inconsistent accuracy due to limitations with their training dataset. LLMs are "teachable" through customization. We compared the ability of the generic ChatGPT-4 model and a cus...

A Machine Learning Predictive Model for Ureteroscopy Lasertripsy Outcomes in a Pediatric Population-Results from a Large Endourology Tertiary Center.

Journal of endourology
We aimed to develop machine learning (ML) algorithms for the automated prediction of postoperative ureteroscopy outcomes for pediatric kidney stones based on preoperative characteristics. Data from pediatric patients who underwent ureteroscopy for ...

High-Throughput Deep Learning Detection of Mitral Regurgitation.

Circulation
BACKGROUND: Diagnosis of mitral regurgitation (MR) requires careful evaluation by echocardiography with Doppler imaging. This study presents the development and validation of a fully automated deep learning pipeline for identifying apical 4-chamber v...

Prediction of neurologic outcome after out-of-hospital cardiac arrest: An interpretable approach with machine learning.

Resuscitation
UNLABELLED: Out-of-hospital cardiac arrest (OHCA) is a critical condition with low survival rates. In patients with a return of spontaneous circulation, brain injury is a leading cause of death. In this study, we propose an interpretable machine lear...

Utilizing machine learning to integrate single-cell and bulk RNA sequencing data for constructing and validating a novel cell adhesion molecules related prognostic model in gastric cancer.

Computers in biology and medicine
BACKGROUND: Cell adhesion molecules (CAMs) play a vital role in cell-cell interactions, immune response modulation, and tumor cell migration. However, the unique role of CAMs in gastric cancer (GC) remains largely unexplored.

Capability of multimodal large language models to interpret pediatric radiological images.

Pediatric radiology
BACKGROUND: There is a dearth of artificial intelligence (AI) development and research dedicated to pediatric radiology. The newest iterations of large language models (LLMs) like ChatGPT can process image and video input in addition to text. They ar...

Assessment of EMR ML Mining Methods for Measuring Association between Metal Mixture and Mortality for Hypertension.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension
INTRODUCTION: There are limited data available regarding the connection between heavy metal exposure and mortality among hypertension patients.

Feedback control of heart rate during robotics-assisted tilt table exercise in patients after stroke: a clinical feasibility study.

Journal of neuroengineering and rehabilitation
BACKGROUND: Patients with neurological disorders including stroke use rehabilitation to improve cognitive abilities, to regain motor function and to reduce the risk of further complications. Robotics-assisted tilt table technology has been developed ...

Artificial intelligence reveals the predictions of hematological indexes in children with acute leukemia.

BMC cancer
Childhood leukemia is a prevalent form of pediatric cancer, with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) being the primary manifestations. Timely treatment has significantly enhanced survival rates for children with acute ...