AIMC Topic: Gastrointestinal Microbiome
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Machine learning algorithms reveal gut microbiota signatures associated with chronic hepatitis B-related hepatic fibrosis.
World journal of gastroenterology
Apr 28, 2025
BACKGROUND: Hepatic fibrosis (HF) represents a pivotal stage in the progression and potential reversal of cirrhosis, underscoring the importance of early identification and therapeutic intervention to modulate disease trajectory.
AI and Machine Learning Computational Modeling that Takes into Consideration Gut Microbiota for a Personalized Decision Support Preoperative Planning for an Optimum Liver Regeneration After Partial Hepatectomy.
Studies in health technology and informatics
Apr 8, 2025
INTRODUCTION: Gut microbiota (GM) is implicated in the remnant liver regeneration (LR) after partial hepatectomy (PH) and affects outcomes. Our study shifts the algorithmic computational modeling from the classical knowledge of (LR) to that of (GM) i...
Using gut microbiome metagenomic hypervariable features for diabetes screening and typing through supervised machine learning.
Microbial genomics
Mar 1, 2025
Diabetes mellitus is a complex metabolic disorder and one of the fastest-growing global public health concerns. The gut microbiota is implicated in the pathophysiology of various diseases, including diabetes. This study utilized 16S rRNA metagenomic ...
A novel approach to finding the compositional differences and biomarkers in gut microbiota in type 2 diabetic patients via meta-analysis, data-mining, and multivariate analysis.
Endocrinologia, diabetes y nutricion
Jan 1, 2025
BACKGROUND/PURPOSE OF THE STUDY: Type 2 diabetes mellitus (T2DM)-one of the fastest globally spreading diseases-is a chronic metabolic disorder characterized by elevated blood glucose levels. It has been suggested that the composition of gut microbio...
AI-driven multi-omics profiling of sepsis immunity in the digestive system.
Frontiers in immunology
Jan 1, 2025
Sepsis is a life-threatening systemic inflammatory syndrome characterized by a complex immune biphasic imbalance. Monitoring of immune status has not yet been implemented in clinical practice due to lack of direct therapeutic utility. Immune dysregul...
A machine-learning approach for predicting butyrate production by microbial consortia using metabolic network information.
PeerJ
Jan 1, 2025
Understanding the behavior of microbial consortia is crucial for predicting metabolite production by microorganisms. Genome-scale network reconstructions enable the computation of metabolic interactions and specific associations within microbial cons...
Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling.
Frontiers in immunology
Jan 1, 2025
The important function of microbiota as therapeutic modulators and diagnostic biomarkers in cancer has been shown by recent developments in microbiome research. The intricate interplay between the gut microbiota and the development of cancer, especia...
The role of the microbiota-gut-brain axis and artificial intelligence in cognitive health of pediatric obstructive sleep apnea: A narrative review.
Medicine
Dec 13, 2024
Pediatric obstructive sleep apnea (OSA) is a prevalent sleep-related breathing disorder associated with significant neurocognitive and behavioral impairments. Recent studies have highlighted the role of gut microbiota and the microbiota-gut-brain axi...
MicroHDF: predicting host phenotypes with metagenomic data using a deep forest-based framework.
Briefings in bioinformatics
Sep 23, 2024
The gut microbiota plays a vital role in human health, and significant effort has been made to predict human phenotypes, especially diseases, with the microbiota as a promising indicator or predictor with machine learning (ML) methods. However, the a...
Predicting the role of the human gut microbiome in type 1 diabetes using machine-learning methods.
Briefings in functional genomics
Jul 19, 2024
Gut microbes is a crucial factor in the pathogenesis of type 1 diabetes (T1D). However, it is still unclear which gut microbiota are the key factors affecting T1D and their influence on the development and progression of the disease. To fill these kn...
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