AIMC Topic: Glaucoma
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GAINSeq: glaucoma pre-symptomatic detection using machine learning models driven by next-generation sequencing data.
Scientific reports
Jul 2, 2025
Congenital glaucoma, a complex and diverse condition, presents considerable difficulties in its identification and categorization. This research used Next Generation Sequencing (NGS) whole-exome data to create a categorization framework using machine...
Analysis of 2-dimensional regional differences in the peripapillary scleral fibroblast cytoskeleton of normotensive and hypertensive mouse eyes.
Scientific reports
Jul 1, 2025
These studies aimed to study the mechanisms of glaucomatous peripapillary scleral (PPS) remodeling by investigating IOP-induced changes in fibroblast actin-collagen alignment and nuclear morphology in mouse PPS. Cryosections from the optic nerve head...
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International ophthalmology
Jun 27, 2025
UNLABELLED: Early detection of glaucoma represents a vital factor in securing vision while the disease retains its position as one of the central causes of blindness worldwide. The current glaucoma screening strategies with expert interpretation depe...
Evaluating real-world performance of an automated offline glaucoma AI on a smartphone fundus camera across glaucoma severity stages.
PloS one
Jun 26, 2025
PURPOSE: Leveraging an artificial intelligence system (AI) for glaucoma screening can mitigate the current challenges and provide prompt detection and management crucial in averting irreversible blindness. The study reports the real-world performance...
Artificial intelligence for glaucoma.
The Cochrane database of systematic reviews
Jun 17, 2025
This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: To determine the accuracy of artificial intelligence (AI) algorithms as a diagnostic tool for glaucoma compared with human graders in a community or secondary care ...
Deep learning-assisted 10-μL single droplet-based viscometry for human aqueous humor.
Biosensors & bioelectronics
May 2, 2025
Probing the viscosity of human aqueous humor is crucial for optimizing micro-tube shunts in glaucoma treatment. However, conventional viscometers are not suitable for aqueous humor due to the limited sample volume-only tens of microliters-that can be...
Enhanced glaucoma classification through advanced segmentation by integrating cup-to-disc ratio and neuro-retinal rim features.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Apr 28, 2025
Glaucoma is a progressive eye condition caused by high intraocular fluid pressure, damaging the optic nerve, leading to gradual, irreversible vision loss, often without noticeable symptoms. Subtle signs like mild eye redness, slightly blurred vision,...
Risk for ocular hypertension progression to early glaucoma: A predictive model and key predictors.
Photodiagnosis and photodynamic therapy
Apr 28, 2025
BACKGROUND: Ocular hypertension (OHT) is the most significant risk factor for glaucoma. We aimed to develop a model for predicting OHT progression to early glaucoma and to identify key predictors.
Optimized glaucoma detection using HCCNN with PSO-driven hyperparameter tuning.
Biomedical physics & engineering express
Apr 22, 2025
. This study is focused on creating an effective glaucoma detection system employing a Hybrid Centric Convolutional Neural Network (HCCNN) model. By using Particle Swarm Optimization (PSO), classification accuracy is increased and computing complexit...
Automated learning of glaucomatous visual fields from OCT images using a comprehensive, segmentation-free 3D convolutional neural network model.
Scientific reports
Apr 18, 2025
A segmentation-free 3D Convolutional Neural Network (3DCNN) model was adopted to estimate Visual Field (VF) in glaucoma cases using Optical Coherence Tomography (OCT) images. This study, conducted at a university hospital, included 6335 participants ...
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