AIMC Topic: Glioma

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An effective flowchart for multimodal brain tumor binary classification with ranked 3D texture features.

Scientific reports
Brain tumors have complex structures, and their shape, density, and size can vary widely. Consequently, their accurate classification, which involves identifying features that best describe the tumor data, is challenging. Using classical 2D texture f...

Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.

Scientific reports
Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Con...

Building simplified cancer subtyping and prediction models with glycan gene signatures.

Cell reports methods
We identified a gene panel comprising 71 glycosyltransferases (GTs) that alter glycan patterns on cancer cells as they become more virulent. When these cancer-pattern GTs (CPGTs) were run through an algorithm trained on The Cancer Genome Atlas, they ...

Multimodal radiomics in glioma: predicting recurrence in the peritumoural brain zone using integrated MRI.

BMC medical imaging
BACKGROUND: Gliomas exhibit a high recurrence rate, particularly in the peritumoural brain zone after surgery. This study aims to develop and validate a radiomics-based model using preoperative fluid-attenuated inversion recovery (FLAIR) and T1-weigh...

Phenotype augmentation using generative AI for isocitrate dehydrogenase mutation prediction in glioma.

Scientific reports
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...

Machine learning derived development and validation of extracellular matrix related signature for predicting prognosis in adolescents and young adults glioma.

Scientific reports
The mortality rates have been increasing for glioma in adolescents and young adults (AYAs, aged 15-39 years). However, current biomarkers for clinical assessment in AYAs glioma are limited, prompting the urgent need for identifying ideal prognostic s...

Artificial intelligence algorithms for differentiating pseudoprogression from true progression in high-grade gliomas: A systematic review and meta-analysis.

Neurosurgical review
Differentiating pseudoprogression (PsP) from true progression (TP) in high-grade glioma (HGG) patients is still challenging and critical for effective treatment management. This meta-analysis evaluates the diagnostic accuracy of artificial intelligen...

Pyramidal attention-based T network for brain tumor classification: a comprehensive analysis of transfer learning approaches for clinically reliable and reliable AI hybrid approaches.

Scientific reports
Brain tumors are a significant challenge to human health as they impair the proper functioning of the brain and the general quality of life, thus requiring clinical intervention through early and accurate diagnosis. Although current state-of-the-art ...

Machine learning of whole-brain resting-state fMRI signatures for individualized grading of frontal gliomas.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: Accurate preoperative grading of gliomas is critical for therapeutic planning and prognostic evaluation. We developed a noninvasive machine learning model leveraging whole-brain resting-state functional magnetic resonance imaging (rs-fMRI) b...

Open-radiomics: a collection of standardized datasets and a technical protocol for reproducible radiomics machine learning pipelines.

BMC medical imaging
BACKGROUND: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along with a co...