AIMC Topic: Glioma

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Predicting therapeutic clinical trial enrollment for adult patients with low- and high-grade glioma using supervised machine learning.

Science advances
Therapeutic clinical trial enrollment does not match glioma incidence across demographics. Traditional statistical methods have identified independent predictors of trial enrollment; however, our understanding of the interactions between these factor...

Super-resolution sodium MRI of human gliomas at 3T using physics-based generative artificial intelligence.

Journal of neuro-oncology
PURPOSE: Sodium neuroimaging provides unique insights into the cellular and metabolic properties of brain tumors. However, at 3T, sodium neuroimaging MRI's low signal-to-noise ratio (SNR) and resolution discourages routine clinical use. We evaluated ...

Current trends in glioma tumor segmentation: A survey of deep learning modules.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND: Multiparametric Magnetic Resonance Imaging (mpMRI) is the gold standard for diagnosing brain tumors, especially gliomas, which are difficult to segment due to their heterogeneity and varied sub-regions. While manual segmentation is time-c...

Morphometric and radiomics analysis toward the prediction of epilepsy associated with supratentorial low-grade glioma in children.

Cancer imaging : the official publication of the International Cancer Imaging Society
OBJECTIVES: Understanding the impact of epilepsy on pediatric brain tumors is crucial to diagnostic precision and optimal treatment selection. This study investigated MRI radiomics features, tumor location, voxel-based morphometry (VBM) for gray matt...

Semisupervised adaptive learning models for IDH1 mutation status prediction.

PloS one
The mutation status of isocitrate dehydrogenase1 (IDH1) in glioma is critical information for the diagnosis, treatment, and prognosis. Accurately determining such information from MRI data has emerged as a significant research challenge in recent yea...

Brain tumor detection empowered with ensemble deep learning approaches from MRI scan images.

Scientific reports
Brain tumor detection is essential for early diagnosis and successful treatment, both of which can significantly enhance patient outcomes. To evaluate brain MRI scans and categorize them into four types-pituitary, meningioma, glioma, and normal-this ...

From pixels to prognosis: leveraging radiomics and machine learning to predict IDH1 genotype in gliomas.

Neurosurgical review
Gliomas are the most common primary tumors of the central nervous system, and advances in genetics and molecular medicine have significantly transformed their classification and treatment. This study aims to predict the IDH1 genotype in gliomas using...

UBTD2 protein molecules emerges as a key prognostic protein marker in glioma: Insights from integrated omics and machine learning analysis of GRM7, NCAPG, CEP55, and other biomarkers.

International journal of biological macromolecules
Glioma is a malignant brain tumor with poor prognosis, and there is an urgent need to find effective biomarkers for early diagnosis and treatment. The aim of this study was to explore the potential of UBTD2 as a key prognostic protein marker for glio...

Leveraging TME features and multi-omics data with an advanced deep learning framework for improved Cancer survival prediction.

Scientific reports
Glioma, a malignant intracranial tumor with high invasiveness and heterogeneity, significantly impacts patient survival. This study integrates multi-omics data to improve prognostic prediction and identify therapeutic targets. Using single-cell data ...