Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Nov 6, 2024
BACKGROUND: Promptable foundation auto-segmentation models like Segment Anything (SA, Meta AI, New York, USA) represent a novel class of universal deep learning auto-segmentation models that could be employed for interactive tumor auto-contouring in ...
BACKGROUND: Glioma is a highly heterogeneous and poorly immunogenic malignant tumor, with limited efficacy of immunotherapy. The characteristics of the immunosuppressive tumor microenvironment (TME) are one of the important factors hindering the effe...
Glioblastoma multiforme (GBM) is one of the most common and aggressive type of malignant glioma with an average survival time of 12-18 mo. Despite the utilization of extensive surgical resections using cutting-edge neuroimaging, and advanced chemothe...
BACKGROUND: Despite advances in neuro-oncology, treatments of glioma and tools for predicting the outcome of patients remain limited. The objective of this research is to construct a prognostic model for glioma using the Homologous Recombination Defi...
International journal of radiation oncology, biology, physics
Oct 1, 2024
PURPOSE: Magnetic resonance (MR)-guided radiation therapy enables online adaptation to address intra- and interfractional changes. To address the need of high-fidelity synthetic computed tomography (synCT) required for dose calculation, we developed ...
Interdisciplinary sciences, computational life sciences
Sep 27, 2024
Diagnosing and classifying central nervous system tumors such as gliomas or glioblastomas pose a significant challenge due to their aggressive and infiltrative nature. However, recent advancements in metabolomics and magnetic resonance spectroscopy (...
OBJECTIVE: Develop a time-dependent deep learning model to accurately predict the prognosis of pediatric glioma patients, which can assist clinicians in making precise treatment decisions and reducing patient risk.
Gliomas are the most common tumor in the central nervous system in adults, with glioblastoma (GBM) representing the most malignant form, while low-grade glioma (LGG) is a less severe. The prognosis for glioma remains poor even after various treatment...
RATIONALE AND OBJECTIVES: Recent radiomics studies on predicting pathological outcomes of glioma have shown immense potential. However, the predictive ability remains suboptimal due to the tumor intrinsic heterogeneity. We aimed to achieve better pat...
INTRODUCTION: Gliomas are the most common and aggressive type of primary brain tumor, with a poor prognosis despite current treatment approaches. Understanding the molecular mechanisms underlying glioma development and progression is critical for imp...
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