AIMC Topic: Glioma

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Can we rely on machine learning algorithms as a trustworthy predictor for recurrence in high-grade glioma? A systematic review and meta-analysis.

Clinical neurology and neurosurgery
Early prediction of recurrence in high-grade glioma (HGG) is critical due to its aggressive nature and poor prognosis. Distinguishing true recurrence from treatment-related changes, such as radionecrosis, is a major diagnostic challenge. Machine lear...

An interpretable multi-scale convolutional attention residual neural network for glioma grading with Raman spectroscopy.

Analytical methods : advancing methods and applications
Since the malignancy of gliomas varies with their grade, classifying gliomas of different grades can assist doctors in developing personalized surgical plans during surgery, thereby improving the prognosis. Raman spectroscopy is an optical method for...

Comparative analysis of deep learning and radiomic signatures for overall survival prediction in recurrent high-grade glioma treated with immunotherapy.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Radiomic analysis of quantitative features extracted from segmented medical images can be used for predictive modeling of prognosis in brain tumor patients. Manual segmentation of the tumor components is time-consuming and poses significa...

Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma.

European journal of nuclear medicine and molecular imaging
PURPOSE: Radiomics-based machine learning (ML) models of amino acid positron emission tomography (PET) images have shown efficiency in glioma prediction tasks. However, their clinical impact on physician interpretation remains limited. This study inv...

A hybrid explainable model based on advanced machine learning and deep learning models for classifying brain tumors using MRI images.

Scientific reports
Brain tumors present a significant global health challenge, and their early detection and accurate classification are crucial for effective treatment strategies. This study presents a novel approach combining a lightweight parallel depthwise separabl...

Diagnostic Accuracy of Ambient Mass Spectrometry with Blood Plasma in a Murine Glioma Model Using Machine Learning.

World neurosurgery
OBJECTIVE: Malignant glioma progresses rapidly and shows poor prognosis, but clinically applicable blood plasma-based biochemical tumor markers remain lacking. This study aimed to develop a diagnostic system using probe electrospray ionization mass s...

Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks.

Scientific reports
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of ...

Impact of glioma metabolism-related gene ALPK1 on tumor immune heterogeneity and the regulation of the TGF-β pathway.

Frontiers in immunology
BACKGROUND: Recent years have seen persistently poor prognoses for glioma patients. Therefore, exploring the molecular subtyping of gliomas, identifying novel prognostic biomarkers, and understanding the characteristics of their immune microenvironme...

Dual-path neural network extracts tumor microenvironment information from whole slide images to predict molecular typing and prognosis of Glioma.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Utilizing AI to mine tumor microenvironment information in whole slide images (WSIs) for glioma molecular subtype and prognosis prediction is significant for treatment. Existing weakly-supervised learning frameworks based on...

Weakly supervised deep learning-based classification for histopathology of gliomas: a single center experience.

Scientific reports
Multiple artificial intelligence systems have been created to facilitate accurate and prompt histopathological diagnosis of tumors using hematoxylin-eosin-stained slides. We aimed to investigate whether weakly supervised deep learning can aid in glio...