AIMC Topic: Gold

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Active capture-directed bimetallic nanosubstrate for enhanced SERS detection of Staphylococcus aureus by combining strand exchange amplification and wavelength-selective machine learning.

Biosensors & bioelectronics
Staphylococcus aureus (S. aureus) is the leading risk factor for food safety and human health. Herein, a novel wavelength-selective machine learning -driven adaptive strand exchange amplification (SEA)/SERS biosensor was developed for rapid detection...

SERS based determination of ceftriaxone, ampicillin, and vancomycin in serum using WS/Au@Ag nanocomposites and a 2D-CNN regression model.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Accurate therapeutic drug monitoring (TDM) of antibiotics including ceftriaxone, ampicillin, and vancomycin plays an important role in the treatment of neonatal sepsis, a common and life-threatening disease in neonates. A highly sensitive surface-enh...

Artificial intelligence enhanced microfluidic system for multiplexed point-of-care-testing of biological thiols.

Talanta
Cysteamine (CA) serves as a cystine-depleting agent employed in the management of cystinosis and a range of other medical conditions. Monitoring blood CA levels at the point of care is imperative due to the risk of toxicity associated with elevated C...

A machine-learning-integrated portable electrochemiluminescence sensing platform for the visualization and high-throughput immunoassays.

Talanta
Electrochemiluminescence (ECL)-based point-of-care testing (POCT) has the potential to facilitate the rapid identification of diseases, offering advantages such as high sensitivity, strong selectivity, and minimal background interference. However, as...

Optoelectronic-Coupled-Driven Microrobot for Biological Cargo Transport in Conductive Isosmotic Glucose Solution.

ACS applied materials & interfaces
Electric field-driven micro/nanorobots, as micro/nanodevices with autonomous motion capability, have emerged as promising candidates for targeted cargo delivery in biomedical applications due to their advantages of label-free operation, selectivity, ...

Deep Learning-Based TEM Image Analysis for Fully Automated Detection of Gold Nanoparticles Internalized Within Tumor Cell.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Transmission electron microscopy (TEM) imaging can be used for detection/localization of gold nanoparticles (GNPs) within tumor cells. However, quantitative analysis of GNP-containing cellular TEM images typically relies on conventional/thresholding-...

quEHRy: a question answering system to query electronic health records.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: We propose a system, quEHRy, to retrieve precise, interpretable answers to natural language questions from structured data in electronic health records (EHRs).

Deep-Learning Electron Diffractive Imaging.

Physical review letters
We report the development of deep-learning coherent electron diffractive imaging at subangstrom resolution using convolutional neural networks (CNNs) trained with only simulated data. We experimentally demonstrate this method by applying the trained ...

Gold-viral particle identification by deep learning in wide-field photon scattering parametric images.

Applied optics
The ability to identify virus particles is important for research and clinical applications. Because of the optical diffraction limit, conventional optical microscopes are generally not suitable for virus particle detection, and higher resolution ins...

Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder.

Science robotics
Enzyme-powered nanomotors are an exciting technology for biomedical applications due to their ability to navigate within biological environments using endogenous fuels. However, limited studies into their collective behavior and demonstrations of tra...