AIMC Topic: Gray Matter
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Multivariate brain morphological patterns across mood disorders: key roles of frontotemporal and cerebellar areas.
BMJ mental health
Jun 10, 2025
BACKGROUND: Differentiating major depressive disorder (MDD) from bipolar disorder (BD) remains a significant clinical challenge, as both disorders exhibit overlapping symptoms but require distinct treatment approaches. Advances in voxel-based morphom...
Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort.
eLife
May 29, 2025
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.
Predicting treatment response in individuals with major depressive disorder using structural MRI-based similarity features.
BMC psychiatry
May 26, 2025
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
Joint resting state and structural networks characterize pediatric bipolar patients compared to healthy controls: a multimodal fusion approach.
NeuroImage
Apr 17, 2025
Pediatric bipolar disorder (PBD) is a highly debilitating condition, characterized by alternating episodes of mania and depression, with intervening periods of remission. Limited information is available about the functional and structural abnormalit...
Structural brain pattern abnormalities in tinnitus with and without hearing loss.
Hearing research
Apr 6, 2025
OBJECTIVE: Subjective tinnitus often coexists with hearing loss, and they share common pathophysiological mechanisms. This comorbidity induces whole-brain gray matter volume (GMV) alterations, manifesting as distributed structural changes in neural n...
Comprehensive Segmentation of Gray Matter Structures on T1-Weighted Brain MRI: A Comparative Study of Convolutional Neural Network, Convolutional Neural Network Hybrid-Transformer or -Mamba Architectures.
AJNR. American journal of neuroradiology
Apr 2, 2025
BACKGROUND AND PURPOSE: Recent advances in deep learning have shown promising results in medical image analysis and segmentation. However, most brain MRI segmentation models are limited by the size of their data sets and/or the number of structures t...
Dynamic glucose enhanced imaging using direct water saturation.
Magnetic resonance in medicine
Mar 17, 2025
PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based li...
A comprehensive approach to anticipating the progression of mild cognitive impairment.
Brain research
Mar 6, 2025
The immersive experience provided by our approach empowers researchers with an intuitive exploration of brain structures. Within the brain's central nervous system, encompassing both white and gray matter, symptoms associated with Alzheimer's disease...
Enhanced U-Net for Infant Brain MRI Segmentation: A (2+1)D Convolutional Approach.
Sensors (Basel, Switzerland)
Feb 28, 2025
BACKGROUND: Infant brain tissue segmentation from MRI data is a critical task in medical imaging, particularly challenging due to the evolving nature of tissue contrasts in the early months of life. The difficulty increases as gray matter (GM) and wh...
Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation-Based Morphometry Study.
Annals of neurology
Feb 22, 2025
OBJECTIVE: Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve i...
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