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Head and Neck Neoplasms

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Democratizing cancer detection: artificial intelligence-enhanced endoscopy could address global disparities in head and neck cancer outcomes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
INTRODUCTION: This article explores the potential role of artificial intelligence (AI) in enhancing the early detection and diagnosis of head and neck squamous cell carcinoma (HNSCC).

Development and validation of MRI-derived deep learning score for non-invasive prediction of PD-L1 expression and prognostic stratification in head and neck squamous cell carcinoma.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Immunotherapy has revolutionized the treatment landscape for head and neck squamous cell carcinoma (HNSCC) and PD-L1 combined positivity score (CPS) scoring is recommended as a biomarker for immunotherapy. Therefore, this study aimed to d...

Machine learning explainability for survival outcome in head and neck squamous cell carcinoma.

International journal of medical informatics
BACKGROUND: Diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) induces psychological variables and treatment-related toxicity in patients. The evaluation of outcomes is warranted for effective treatment planning and improved dis...

Geometric and Dosimetric Evaluation of a RayStation Deep Learning Model for Auto-Segmentation of Organs at Risk in a Real-World Head and Neck Cancer Dataset.

Clinical oncology (Royal College of Radiologists (Great Britain))
AIMS: To assess geometric accuracy and dosimetric impact of a deep learning segmentation (DLS) model on a large, diverse dataset of head and neck cancer (HNC) patients treated with intensity-modulated proton therapy (IMPT).

Closing the gap in plan quality: Leveraging deep-learning dose prediction for adaptive radiotherapy.

Journal of applied clinical medical physics
PURPOSE: Balancing quality and efficiency has been a challenge for online adaptive therapy. Most systems start the online re-optimization with the original planning goals. While some systems allow planners to modify the planning goals, achieving a hi...

Deep learning techniques for proton dose prediction across multiple anatomical sites and variable beam configurations.

Physics in medicine and biology
To evaluate the impact of beam mask implementation and data aggregation on artificial intelligence-based dose prediction accuracy in proton therapy, with a focus on scenarios involving limited or highly heterogeneous datasets.In this study, 541 prost...

Enhanced dose prediction for head and neck cancer artificial intelligence-driven radiotherapy based on transfer learning with limited training data.

Journal of applied clinical medical physics
PURPOSE: Training deep learning dose prediction models for the latest cutting-edge radiotherapy techniques, such as AI-based nodal radiotherapy (AINRT) and Daily Adaptive AI-based nodal radiotherapy (DA-AINRT), is challenging due to limited data. Thi...

Deep learning-based segmentation of head and neck organs at risk on CBCT images with dosimetric assessment for radiotherapy.

Physics in medicine and biology
Cone beam computed tomography (CBCT) has become an essential tool in head and neck cancer (HNC) radiotherapy (RT) treatment delivery. Automatic segmentation of the organs at risk (OARs) on CBCT can trigger and accelerate treatment replanning but is s...

Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas.

Oral oncology
OBJECTIVES: Human papillomavirus (HPV) influences the pathobiology of Head and Neck Squamous Cell Carcinomas (HSNCCs). While deep learning shows promise in detecting HPV from hematoxylin and eosin (H&E) stained slides, the histologic features utilize...

A deep learning model for inter-fraction head and neck anatomical changes in proton therapy.

Physics in medicine and biology
To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients.A probabilistic daily anatomy model (DAM) for head and neck patients DAM (DAM) is built on the varia...