AIMC Topic: Head and Neck Neoplasms

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Reliability of uncertainty quantification methods for deep learning auto-segmentation in head and neck organs at risk.

Physics in medicine and biology
Deep learning auto-segmentation has greatly advanced contouring in radiotherapy. However, quality assurance remains necessary due to performance fluctuation among individual patients. This manual process reintroduces variability and partially reduces...

Predicting outcomes in head and neck cancer using CT images via transfer learning.

BMC medical imaging
BACKGROUND: Accurate preoperative risk stratification for patients with head and neck (H&N) cancer remained a critical challenge, as long-term survival rates are poor despite aggressive multimodality treatment. While deep learning models showed promi...

Wearable Technologies in Head and Neck Oncology: Scoping Review.

JMIR mHealth and uHealth
BACKGROUND: Head and neck cancer (HNC) survivors face profound functional and quality-of-life deficits due to disease- and treatment-related sequelae, ranging from mild fatigue to debilitating dysphagia. Wearable technology, by monitoring biometric d...

Assessing the feasibility of deep learning-based attenuation correction using photon emission data inF-FDG images for dedicated head and neck PET scanners.

Biomedical physics & engineering express
This study aimed to evaluate the use of deep learning techniques to produce measured attenuation-corrected (MAC) images from non-attenuation-corrected (NAC) F-FDG PET images, focusing on head and neck imaging. A Residual Network (ResNet) was used to ...

CNN-based prediction using early post-radiotherapy MRI as a proxy for toxicity in the murine head and neck.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Radiotherapy (RT) of head and neck cancer can cause severe toxicities. Early identification of individuals at risk could enable personalized treatment. This study evaluated whether convolutional neural networks (CNNs) applied ...

Prognostic models for radiation-induced complications after radiotherapy in head and neck cancer patients.

The Cochrane database of systematic reviews
BACKGROUND: Radiotherapy is the mainstay of treatment for head and neck cancer (HNC) but may induce various side effects on surrounding normal tissues. To reach an optimal balance between tumour control and toxicity prevention, normal tissue complica...

External validation of deep learning-derived 18F-FDG PET/CT delta biomarkers for loco-regional control in head and neck cancer.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Delta biomarkers that reflect changes in tumour burden over time can support personalised follow-up in head and neck cancer. However, their clinical use can be limited by the need for manual image segmentation. This study exte...

Cancer care coordination determinants of depression in head and neck cancer survivors.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: This study aims to explore the role of patient-reported cancer care coordination in explaining depression among head and neck (HNC) cancer survivors.

Comprehensive integration of single-cell and bulk transcriptome to reveal plasma cell heterogeneity and a prognosis signature in head and neck squamous cell carcinoma.

Oral oncology
Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignancy with a low five-year survival rate, emphasising the urgent need for effective prognostic biomarkers to guide patient stratification and personalised treatment. Plasma cells (PCs)...

Network-based approach identifies key genes associated with tumor heterogeneity in HPV positive and negative head and neck cancer patients.

Scientific reports
Head and Neck Squamous Cell Carcinoma (HNSCC) is the seventh most prevalent cancer worldwide and is classified as human papillomavirus (HPV) positive or negative. Substantial heterogeneity has been observed in the two groups, posing a significant cli...