AIMC Topic: Heart Failure

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Continuous-Flow Left Ventricular Assist Devices and Valvular Heart Disease: A Comprehensive Review.

The Canadian journal of cardiology
Mechanical circulatory support with implantable durable continuous-flow left ventricular assist devices (CF-LVADs) represents an established surgical treatment option for patients with advanced heart failure refractory to guideline-directed medical t...

ECG AI-Guided Screening for Low Ejection Fraction (EAGLE): Rationale and design of a pragmatic cluster randomized trial.

American heart journal
BACKGROUND: A deep learning algorithm to detect low ejection fraction (EF) using routine 12-lead electrocardiogram (ECG) has recently been developed and validated. The algorithm was incorporated into the electronic health record (EHR) to automaticall...

Clinical Significance of Circulating Cardiomyocyte-Specific Cell-Free DNA in Patients With Heart Failure: A Proof-of-Concept Study.

The Canadian journal of cardiology
We investigated clinical significance of cell-free DNA (cfDNA) in heart failure. This study enrolled 32 heart failure patients and 28 control subjects. Total cfDNA levels were not different between groups (P = 0.343). Bisulfite-digital polymerase cha...

A speckle-tracking strain-based artificial neural network model to differentiate cardiomyopathy type.

Scandinavian cardiovascular journal : SCJ
In heart failure, invasive angiography is often employed to differentiate ischaemic from non-ischaemic cardiomyopathy. We aim to examine the predictive value of echocardiographic strain features alone and in combination with other features to differ...

Deep representation learning for individualized treatment effect estimation using electronic health records.

Journal of biomedical informatics
Utilizing clinical observational data to estimate individualized treatment effects (ITE) is a challenging task, as confounding inevitably exists in clinical data. Most of the existing models for ITE estimation tackle this problem by creating unbiased...

Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction.

JACC. Heart failure
OBJECTIVES: This study sought to develop models for predicting mortality and heart failure (HF) hospitalization for outpatients with HF with preserved ejection fraction (HFpEF) in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with...

Intelligent Imaging: Radiomics and Artificial Neural Networks in Heart Failure.

Journal of medical imaging and radiation sciences
BACKGROUND: Our previous work with iodine meta-iodobenzylguanidine (I-mIBG) radionuclide imaging among patients with cardiomyopathy reported limitations associated with the prognostic power of global parameters derived from planar imaging [1]. Employ...

Readmission prediction using deep learning on electronic health records.

Journal of biomedical informatics
Unscheduled 30-day readmissions are a hallmark of Congestive Heart Failure (CHF) patients that pose significant health risks and escalate care cost. In order to reduce readmissions and curb the cost of care, it is important to initiate targeted inter...