Hemodynamic support in neonatal intensive care is directed at maintaining cardiovascular wellbeing. At present, monitoring of vital signs plays an essential role in augmenting care in a reactive manner. By applying machine learning techniques, a mode...
Proteins carry out the vast majority of functions in all biological domains, but for technological reasons their large-scale investigation has lagged behind the study of genomes. Since the first essentially complete eukaryotic proteome was reported, ...
Neural networks : the official journal of the International Neural Network Society
Feb 1, 2020
The immense complexity of the brain requires that it be built and controlled by intrinsic, self-regulating mechanisms. One such mechanism, the formation of new connections via synaptogenesis, plays a central role in neuronal connectivity and, ultimat...
Nicotinamide adenine dinucleotide (NAD) is an important natural molecule involved in fundamental biological processes, including the TCA cycle, OXPHOS, β-oxidation, and is a co-factor for proteins promoting healthy longevity. NAD depletion is associa...
What is the physiological basis of long-term memory? The prevailing view in Neuroscience attributes changes in synaptic efficacy to memory acquisition, implying that stable memories correspond to stable connectivity patterns. However, an increasing b...
BACKGROUND: Gene-gene interactions (GGIs) are a known cause of missing heritability. Multifactor dimensionality reduction (MDR) is one of most commonly used methods for GGI detection. The generalized multifactor dimensionality reduction (GMDR) method...
In order to survive and reproduce, living organisms must be robust, tolerate injuries and undergo repair. Robustness in living organisms compares to robustness in human inventions, such as buildings and machines, which have to withstand occasional da...
Journal of the Royal Society, Interface
Jan 1, 2018
Obesity is a major global public health problem. Understanding how energy homeostasis is regulated, and can become dysregulated, is crucial for developing new treatments for obesity. Detailed recording of individual behaviour and new imaging modaliti...
Embodied cognition is a hot topic in both cognitive science and AI, despite the fact that there still is relatively little consensus regarding what exactly constitutes 'embodiment'. While most embodied AI and cognitive robotics research views the bod...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Mar 30, 2016
UNLABELLED: Developing neuronal networks display spontaneous bursts of action potentials that are necessary for circuit organization and tuning. While spontaneous activity has been shown to instruct map formation in sensory circuits, it is unknown wh...