AIMC Topic: Humans

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Comparative analysis of machine learning and deep learning algorithms for knee arthritis detection using YOLOv8 models.

Journal of X-ray science and technology
Knee arthritis is a prevalent joint condition that affects many people worldwide. Early detection and appropriate treatment are essential to slow the disease's progression and enhance patients' quality of life. In this study, various machine learning...

Using prognostic signatures and machine learning to identify core features associated with response to CDK4/6 inhibitor-based therapy in metastatic breast cancer.

Oncogene
CDK4/6 inhibitors in combination with endocrine therapy are widely used to treat HR+/HER2- metastatic breast cancer leading to improved progression-free survival (PFS) compared to single agent endocrine therapy. Over 300 patients receiving standard-o...

AI/ML modeling to enhance the capability of in vitro and in vivo tests in predicting human carcinogenicity.

Mutation research. Genetic toxicology and environmental mutagenesis
This study aimed to develop an in silico model for predicting human carcinogenicity using advanced deep learning techniques, specifically Graph Neural Networks (GNN), through a multitask learning (MTL) approach. The MTL framework leveraged auxiliary ...

Post-Mortem imaging biobanks: Building data for reproducibility, standardization, and AI integration.

European journal of radiology
In recent years, post-mortem imaging has advanced with techniques such as Post-Mortem Computed Tomography (PMCT) and Post-Mortem Magnetic Resonance imaging (PMMR). PMCT is particularly useful for assessing skeletal injuries, vascular lesions, and est...

The need for balancing 'black box' systems and explainable artificial intelligence: A necessary implementation in radiology.

European journal of radiology
Radiology is one of the medical specialties most significantly impacted by Artificial Intelligence (AI). AI systems, particularly those employing machine and deep learning, excel in processing large datasets and comparing images from similar contexts...

A compendium of human gene functions derived from evolutionary modelling.

Nature
A comprehensive, computable representation of the functional repertoire of all macromolecules encoded within the human genome is a foundational resource for biology and biomedical research. The Gene Ontology Consortium has been working towards this g...

Deep learning-based LDL-C level prediction and explainable AI interpretation.

Computers in biology and medicine
This study investigates the use of deep learning (DL) models to predict low-density lipoprotein cholesterol (LDL-C) levels. The dataset obtained from New York-Presbyterian Hospital/Weill Cornell Medical Center includes triglycerides (TG), total chole...

Artificial intelligence in medical imaging: From task-specific models to large-scale foundation models.

Chinese medical journal
Artificial intelligence (AI), particularly deep learning, has demonstrated remarkable performance in medical imaging across a variety of modalities, including X-ray, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, positron emi...

GLASSR-Net: Glass Substrate Spectral Restoration Neural Network for Fourier Transform Infrared Microspectroscopy in the Fingerprint Region.

Analytical chemistry
Fourier transform infrared (FTIR) microspectroscopy has emerged as a pivotal pathological tool, offering informative spectral biomarkers for numerous diseases. However, the dependency on specialized infrared (IR) substrates limits effective and wides...

Machine Learning-Aided Intelligent Monitoring of Multivariate miRNA Biomarkers Using Bipolar Self-powered Sensors.

ACS nano
Breast cancer has become the most prevalent form of cancer among women on a global scale. The early and timely diagnosis of breast cancer is of the utmost importance for improving the survival rate of patients with this disease. The occurrence of bre...