AIMC Topic: Humans

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Deep-DPC: Deep learning-assisted label-free temporal imaging discovery of anti-fibrotic compounds by controlling cell morphology.

Journal of advanced research
INTRODUCTION: Fibrosis can damage the normal function of many organs, such as cardiac function, for which no effective clinical therapies exist. However, traditional approaches to anti-fibrosis drug discovery have primarily focused on the final biolo...

The Role of Autophagy and Cell Communication in COPD Progression: Insights from Bioinformatics and scRNA-seq.

COPD
Chronic obstructive pulmonary disease (COPD) is characterized by restricted airflow that leads to significant respiratory difficulties. This progressive disease often results in diminished pulmonary function and the onset of additional respiratory co...

A PET/CT-based 3D deep learning model for predicting spread through air spaces in stage I lung adenocarcinoma.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: This study evaluates a three-dimensional (3D) deep learning (DL) model based on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for predicting the preoperative status of spread through air spa...

Using machine learning to predict poor adherence to antiretroviral therapy among adolescents with HIV in low resource settings.

AIDS (London, England)
OBJECTIVES: Achieving optimal adherence to antiretroviral therapy (ART) and viral suppression is still insufficient for attaining the UNAIDS 95-95-95 target of 2030, especially among adolescents with HIV (AWHIV). This study sought to develop a model ...

DeepTree-AAPred: Binary tree-based deep learning model for anti-angiogenic peptides prediction.

Journal of molecular graphics & modelling
Anti-angiogenic peptides (AAPs) show important potential in tumor therapy by limiting the growth and metastasis of tumor cells. Accurate prediction of AAPs is of very positive significance for the therapeutic efficacy of tumors. The high cost of wet ...

Deep Learning-Enhanced Ultra-high-resolution CT Imaging for Superior Temporal Bone Visualization.

Academic radiology
RATIONALE AND OBJECTIVES: This study assesses the image quality of temporal bone ultra-high-resolution (UHR) Computed tomography (CT) scans in adults and children using hybrid iterative reconstruction (HIR) and a novel, vendor-specific deep learning-...

Recent advances in AI-driven protein-ligand interaction predictions.

Current opinion in structural biology
Structure-based drug discovery is a fundamental approach in modern drug development, leveraging computational models to predict protein-ligand interactions. AI-driven methodologies are significantly improving key aspects of the field, including ligan...

MSTNet: Multi-scale spatial-aware transformer with multi-instance learning for diabetic retinopathy classification.

Medical image analysis
Diabetic retinopathy (DR), the leading cause of vision loss among diabetic adults worldwide, underscores the importance of early detection and timely treatment using fundus images to prevent vision loss. However, existing deep learning methods strugg...

Artificial Intelligence in CT for Predicting Cervical Lymph Node Metastasis in Papillary Thyroid Cancer Patients: A Meta-analysis.

Academic radiology
PURPOSE: This meta-analysis aims to evaluate the diagnostic performance of CT-based artificial intelligence (AI) in diagnosing cervical lymph node metastasis (LNM) of papillary thyroid cancer (PTC).