AIMC Topic: Humans

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Towards robotic laboratory automation Plug & Play: The "LAPP" framework.

SLAS technology
Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technolo...

PixelTopoIS: a pixel-topology-coupled guidewire tip segmentation framework for robot-assisted intervention.

International journal of computer assisted radiology and surgery
PURPOSE: Existing works showed great performance in pixel-level guidewire segmentation. However, topology-level segmentation has not been fully exploited in these works. Guidewire (tip) endpoint localization and (guidewire) loop detection are typical...

Optimizing hepatitis B virus screening in the United States using a simple demographics-based model.

Hepatology (Baltimore, Md.)
BACKGROUND AND AIMS: Chronic hepatitis B (CHB) affects >290 million persons globally, and only 10% have been diagnosed, presenting a severe gap that must be addressed. We developed logistic regression (LR) and machine learning (ML; random forest) mod...

Deep multi-instance transfer learning for pneumothorax classification in chest X-ray images.

Medical physics
PURPOSE: Pneumothorax is a life-threatening emergency that requires immediate treatment. Frontal-view chest X-ray images are typically used for pneumothorax detection in clinical practice. However, manual review of radiographs is time-consuming, labo...

A review of explainable and interpretable AI with applications in COVID-19 imaging.

Medical physics
The development of medical imaging artificial intelligence (AI) systems for evaluating COVID-19 patients has demonstrated potential for improving clinical decision making and assessing patient outcomes during the recent COVID-19 pandemic. These have ...

Comparison of a Kidney Replacement Therapy Risk Score Developed in Kaiser Permanente Northwest vs Estimated Glomerular Filtration Rate in Advanced Chronic Kidney Disease Using Decision Curve Analysis.

The Permanente journal
INTRODUCTION: Use of kidney replacement therapy (KRT) prediction models for guiding arteriovenous fistula (AVF) referrals in advanced chronic kidney disease (CKD) is unknown. We aimed to compare a hypothetical approach using a KRT prediction model de...

Prediction of Blood-Brain Barrier Penetration (BBBP) Based on Molecular Descriptors of the Free-Form and In-Blood-Form Datasets.

Molecules (Basel, Switzerland)
The blood-brain barrier (BBB) controls the entry of chemicals from the blood to the brain. Since brain drugs need to penetrate the BBB, rapid and reliable prediction of BBB penetration (BBBP) is helpful for drug development. In this study, free-form ...

BiLSTM-5mC: A Bidirectional Long Short-Term Memory-Based Approach for Predicting 5-Methylcytosine Sites in Genome-Wide DNA Promoters.

Molecules (Basel, Switzerland)
An important reason of cancer proliferation is the change in DNA methylation patterns, characterized by the localized hypermethylation of the promoters of tumor-suppressor genes together with an overall decrease in the level of 5-methylcytosine (5mC)...

Do comprehensive deep learning algorithms suffer from hidden stratification? A retrospective study on pneumothorax detection in chest radiography.

BMJ open
OBJECTIVES: To evaluate the ability of a commercially available comprehensive chest radiography deep convolutional neural network (DCNN) to detect simple and tension pneumothorax, as stratified by the following subgroups: the presence of an intercost...

Deep learning computer-aided detection system for pneumonia in febrile neutropenia patients: a diagnostic cohort study.

BMC pulmonary medicine
BACKGROUND: Diagnosis of pneumonia is critical in managing patients with febrile neutropenia (FN), however, chest X-ray (CXR) has limited performance in the detection of pneumonia. We aimed to evaluate the performance of a deep learning-based compute...