AIMC Topic: Humans

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Relative importance of socioecological domains to predicting opioid-involved mortality.

PloS one
BACKGROUND: The opioid crisis in the United States is a complex issue with interconnected factors that lead to opioid misuse and opioid-involved mortality. This study assessed the relative importance of different risk factor domains in predicting fat...

Effect of a communication robot in the prevention of postoperative delirium in older persons: A randomized controlled trial.

PloS one
Japan Clinical Trials Registry (jRCT) (URL: https://jrct.mhlw.go.jp; No. jRCT1030250018; date: April 1, 2025; retrospectively registered).

Differentiation of COVID-19 from other types of viral pneumonia and severity scoring on baseline chest radiographs: Comparison of deep learning with multi-reader evaluation.

PloS one
Chest X-ray (CXR) imaging plays a pivotal role in the diagnosis and prognosis of viral pneumonia. However, distinguishing COVID-19 CXRs from other viral infections remains challenging due to highly similar radiographic features. Most existing deep le...

Early warning signals of bipolar relapse: Investigating critical slowing down in smartphone data.

Journal of affective disorders
BACKGROUND: Early warning signals (EWS) based on dynamical systems theory, such as increased autocorrelation (AR) and variance, may indicate impending mood episodes in bipolar disorder (BD). This study examines whether smartphone-based digital phenot...

Hysterectomy as a predictor of depression: A comprehensive analysis using logistic regression and machine learning.

Journal of affective disorders
BACKGROUND: An increasing number of studies have shown that there is an inseparable connection between hysterectomy and occurrence of depression, and the impact on patient's mental health cannot be ignored. Therefore, this study utilized the National...

Advancements in DNA methylation technologies and their application in cancer diagnosis.

Epigenetics
DNA methylation is a common epigenetic modification that maintains the integrity of the DNA sequence while profoundly influencing gene expression and phenotypic variation. Aberrant DNA methylation has been associated with the onset and progression of...

CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses.

Autoimmunity
Cryptorchidism, a common male reproductive disorder characterized by undescended testes, is associated with infertility and increased cancer risk. While its etiology remains incompletely understood, accumulating evidence suggests that immune-inflamma...

Predicting depressive symptoms through social support: a machine learning approach in military populations.

European journal of psychotraumatology
Perceived Social support has been consistently shown to reduce depressive symptoms among military personnel. However, limited research has explored how different types of support, emotional, informational, and instrumental, from multiple sources uni...

The evolving role of multimodal imaging, artificial intelligence and radiomics in the radiologic assessment of immune related adverse events.

Clinical imaging
Immunotherapy, in particular checkpoint blockade, has revolutionized the treatment of many advanced cancers. Imaging plays a critical role in assessing both treatment response and the development of immune toxicities. Both conventional imaging and mo...

Affinity prediction of inhibitor-kinase based on mixture of experts enhanced by multimodal feature semantic analysis.

International journal of biological macromolecules
Accurate identification of inhibitor-kinase binding affinity is crucial for drug discovery. However, many deep learning models often overlook high-order feature information from biological networks and face challenges related to the cold-start proble...