Journal of pharmacokinetics and pharmacodynamics
Dec 16, 2025
The landscape of pharmaceutical research and drug development is undergoing a significant evolution, with Model-Informed Drug Discovery and Development (MID3) as a transformative approach to accelerate innovation. Realizing the full potential of MID3...
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by inflammatory brain lesions, making MRI-based lesion segmentation challenging due to noise, missing data, and limited availability of high-quality labeled images. This paper pres...
The Garden classification, based on X-ray interpretation and established over 50 years ago, remains the standard clinical classification system for femoral neck fractures (FNFs). Yet, this classification has a high interobserver variability of 70%. W...
Psychedelics and meditation are known for their potential to induce personally meaningful and even transformative experiences. However, it is unclear how similar these experiences are, or how they differ from each other. This explorative study used n...
Glioblastoma is characterized by diffuse infiltration, making accurate detection of residual disease essential for improving prognostication and guiding treatment. This study evaluates whether the volume of predicted infiltration, generated by a mach...
Prostate cancer (PCa) progression is driven by complex molecular reprogramming, yet distinguishing indolent from aggressive disease remains a challenge. We performed an integrative transcriptomic analysis of 1232 PCa samples spanning normal prostate ...
BACKGROUND: The integration of artificial intelligence (AI) into dermatology holds promise for education and diagnostic purposes, particularly through image generation, which has not been well studied.
BACKGROUND: In recent years, artificial intelligence (AI) has driven the rapid development of AI mental health chatbots. Most current reviews investigated the effectiveness of rule-based or retrieval-based chatbots. To date, there is no comprehensive...
BACKGROUND: We designed learning assignments for students to develop knowledge, skills, and professional attitudes about generative artificial intelligence (AI) in 2 different Master's level courses in health informatics. Our innovative approach assu...
BACKGROUND: ChatGPT excels in natural language tasks, but its performance in the Chinese National Medical Licensing Examination (NMLE) and Chinese medical education remains underexplored. Meanwhile, Chinese corpus-based large language models (LLMs) s...
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